Journal ArticleDOI
Resveratrol suppresses hepatoma cell invasion independently of its anti-proliferative action
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TLDR
The results suggest that theAnti-invasive activity of resveratrol is independent of the anti-proliferative activity, and that the antioxidative property of res veratrol may be involved in its anti- invasive action.About:
This article is published in Cancer Letters.The article was published on 2001-06-26. It has received 88 citations till now. The article focuses on the topics: Resveratrol & Phytoalexin.read more
Citations
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Role of Resveratrol in Prevention and Therapy of Cancer: Preclinical and Clinical Studies
Bharat B. Aggarwal,Anjana Bhardwaj,Rishi S. Aggarwal,Navindra P. Seeram,Shishir Shishodia,Yasunari Takada +5 more
TL;DR: In vivo, resveratrol blocks the multistep process of carcinogenesis at various stages: it blocks carcinogen activation by inhibiting aryl hydrocarbon-induced CYP1A1 expression and activity, and suppresses tumor initiation, promotion and progression.
Journal ArticleDOI
Natural products for cancer prevention: a global perspective
TL;DR: This review focuses on the many natural products that have been implicated in cancer prevention and that promote human health without recognisable side effects from vegetables, fruits, plant extracts, and herbs.
Journal ArticleDOI
Sustained proliferation in cancer: Mechanisms and novel therapeutic targets
Mark A. Feitelson,Alla Arzumanyan,Rob J. Kulathinal,Stacy W. Blain,Randall F. Holcombe,Jamal Mahajna,Maria Marino,María L. Martínez-Chantar,Roman Nawroth,Isidro Sánchez-García,Dipali Sharma,Neeraj K. Saxena,Neetu Singh,Panagiotis J. Vlachostergios,Shanchun Guo,Kanya Honoki,Hiromasa Fujii,Alexandros G. Georgakilas,Alan Bilsland,Amedeo Amedei,Elena Niccolai,Amr Amin,S. Salman Ashraf,Chandra S. Boosani,Gunjan Guha,Maria Rosa Ciriolo,Katia Aquilano,Sophie Chen,Sulma I. Mohammed,Asfar S. Azmi,Dipita Bhakta,Dorota Halicka,W. Nicol Keith,Somaira Nowsheen +33 more
TL;DR: Natural compounds found to inhibit one or more pathways that contribute to proliferation have been found and will be very important for identifying signaling pathways and molecular targets that may provide early diagnostic markers and/or critical targets for the development of new drugs or drug combinations that block tumor formation and progression.
Journal ArticleDOI
Chemopreventive effects of dietary phytochemicals against cancer invasion and metastasis: phenolic acids, monophenol, polyphenol, and their derivatives.
Chia-Jui Weng,Gow-Chin Yen +1 more
TL;DR: It is concluded that the daily consumption of natural dietary components that are rich in phenolics could be beneficial for the prevention of cancer metastasis.
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Melissa officinalis L. essential oil: antitumoral and antioxidant activities.
Allyne Carvalho de Sousa,Daniela S. Alviano,Arie Fitzgerald Blank,Péricles Barreto Alves,Celuta S. Alviano,Cerli Rocha Gattass +5 more
TL;DR: An in‐vitro cytotoxicity assay using MTT indicated that this oil was very effective against a series of human cancer cell lines, and results pointed to the potential use of M. officinalis essential oil as an antitumoral agent.
References
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Journal ArticleDOI
Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes
Mei-Shiang Jang,Lining Cai,George Udeani,Karla Slowing,Cathy F. Thomas,Chris Beecher,Harry H. S. Fong,Norman R. Farnsworth,A. Douglas Kinghorn,Rajendra G. Mehta,Richard C. Moon,John M. Pezzuto +11 more
TL;DR: It is suggested that resveratrol, a common constituent of the human diet, merits investigation as a potential cancer chemopreventive agent in humans.
Journal Article
Tumor invasion and the extracellular matrix.
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Resveratrol, an antioxidant present in red wine, induces apoptosis in human promyelocytic leukemia (HL-60) cells
TL;DR: It is found that resveratrol reduces viability and DNA synthesis capability of cultured human promyelocytic leukemia (HL-60) cells and is suggested to have cancer therapeutic as well as chemopreventive potential.
Journal ArticleDOI
Resveratrol, a Natural Product Present in Wine, Decreases Tumour Growth in a Rat Tumour Model
TL;DR: Interestingly, flow cytometric analysis of the tumour cell population revealed the existence of an aneuploid peak, which suggests that resveratrol causes apoptosis in the tumours cell population resulting in a decreased cell number.
Journal ArticleDOI
Resveratrol prevents apoptosis in K562 cells by inhibiting lipoxygenase and cyclooxygenase activity
TL;DR: The results reported here suggest that the anti-apoptotic activity of resveratrol depends on the direct inhibition of the main arachidonate-metabolizing enzymes.
Related Papers (5)
Resveratrol Isolated from Polygonum cuspidatum Root Prevents Tumor Growth and Metastasis to Lung and Tumor-Induced Neovascularization in Lewis Lung Carcinoma-Bearing Mice
Yoshiyuki Kimura,Hiromichi Okuda +1 more