Journal ArticleDOI
Risk for Malignancy of Thyroid Nodules as Assessed by Sonographic Criteria The Need for Biopsy
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TLDR
This study indicates that the presence of intrinsic microcalcification is the only statistically reliable criterion on which to base increased suspicion for malignancy in thyroid nodules, particularly if calcifications have a snowstorm appearance on sonography.Abstract:
Objective. To correlate sonographic and color Doppler characteristics of thyroid nodules with the results of sonographically guided fine-needle aspiration biopsy to establish the relative importance of these features in predicting risk for malignancy. Methods. We retrospectively analyzed the sonographic features of 34 malignant and 36 benign thyroid nodules with respect to size, echogenicity, echo structure, shape, border, calcification, and internal vascularity. Individual features and combinations of features were analyzed for their correlation with benign or malignant disease. A comparative analysis of several authors' previously proposed methods for distinguishing between benign and malignant nodules using sonographic criteria was also performed to determine their sensitivity and specificity in predicting nodule disease within our study data. Results. Nodule size ranged from 0.8 to 4.6 cm in greatest dimension (mean, 1.96 cm; SD, 0.877 cm). The prevalence of malignancy in our study population was estimated to be nearly 5.33%. Intragroup comparison of sonographic features among benign and malignant nodules resulted in identification of intrinsic calcification as the only statistically significant predictor of malignancy (35.3% sensitive and 94.4% specific; P <.005). Presence of a "snowstorm" pattern of calcification was 100% specific for malignancy. Echogenicity, echo structure, shape, border classification, and grade of internal vascularity did not show any significant difference between benign and malignant nodules in this study. Various combinations of features previously suggested to be significant predictors of malignancy were also analyzed and shown to have very little sensitivity or specificity in predicting benign or malignant disease among nodules in our study population. Conclusions. This study indicates that the presence of intrinsic microcalcification is the only statistically reliable criterion on which to base increased suspicion for malignancy in thyroid nodules. Our results indicate the need for biopsy in determining further workup. All nodules that show the presence of intrinsic microcalcification should undergo biopsy, particularly if calcifications have a snowstorm appearance on sonography.read more
Citations
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Journal ArticleDOI
Thyroid Nodules in Pediatric Patients: Sonographic Characteristics and Likelihood of Cancer
Danielle M Richman,Carol B. Benson,Peter M. Doubilet,Hope E. Peters,Stephen A. Huang,Elizabeth Asch,Ari J. Wassner,Jessica Smith,Christine E Cherella,Mary C. Frates +9 more
TL;DR: Thyroid nodules in patients younger than 19 years that underwent ultrasound (US)-guided fine-needle aspiration biopsy between January 2004 and July 2017 were retrospectively identified to determine the relationship between demographic and sonographic characteristics of thyroid nodules and malignancy in a pediatric population.
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Quantitative Shear Wave Velocity Measurement on Acoustic Radiation Force Impulse Elastography for Differential Diagnosis between Benign and Malignant Thyroid Nodules: A Meta-analysis.
Bo Ji Liu,Dan-Dan Li,Hui-Xiong Xu,Hui-Xiong Xu,Le Hang Guo,Yi Feng Zhang,Jun Mei Xu,Chang Liu,Lin Na Liu,Xiao Long Li,Xiao-Hong Xu,Shen Qu,Mingzhao Xing +12 more
TL;DR: SWV measurement on ARFI elastography has high sensitivity and specificity for differential diagnosis between benign and malignant thyroid nodules and can be used in combination with conventional ultrasound.
Journal Article
The diagnostic efficiency of ultrasound in characterization for thyroid nodules: how many criteria are required to predict malignancy?
Alper Ozel,Sukru Mehmet Erturk,Alkin Ercan,Banu Yilmaz,Tulay Basak,Vito Cantisani,Muzaffer Basak,Zeki Karpat +7 more
TL;DR: Using ultraound, thyroid nodules can be characterized effectively and the number of the US features used in this distinction varies in respect to the nodule size.
Journal ArticleDOI
Vascular pattern and spectral parameters of power Doppler ultrasound as predictors of malignancy risk in thyroid nodules.
Mehdi Bakhshaee,Yasamin Davoudi,Mostafa Mehrabi,Parvin Layegh,Saadat Mirsadaee,Masoud Pezeshki Rad,Parvaneh Leyegh +6 more
TL;DR: Determination whether spectral Doppler ultrasound parameters, including resistance index (RI) and pulsatility index (PI) or vascular pattern can be used to distinguish malignant from benign thyroid nodules is investigated.
Journal ArticleDOI
Role of Duplex Power Doppler Ultrasound in Differentiation between Malignant and Benign Thyroid Nodules
Oktay Algin,Efnan Algin,Gokhan Gokalp,Gokhan Ocakoglu,Cuneyt Erdogan,Ozlem Saraydaroglu,Ercan Tuncel +6 more
TL;DR: Evaluating the usage of duplex power Doppler ultrasound for the differentiation of benign and malignant thyroid nodules found vascularity is not a useful parameter for distinguishing malignant from benign thyroid nodule, however, RI and PI values are useful in distinguishing malign from benign Thyroid nodules.
References
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Journal ArticleDOI
Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color-Doppler features.
Enrico Papini,Rinaldo Guglielmi,Antonio Bianchini,Anna Crescenzi,Silvia Taccogna,Francesco Nardi,Claudio Panunzi,R. Rinaldi,Vincenzo Toscano,Claudio Maurizio Pacella +9 more
TL;DR: The aim of the study was to correlate the sonographic and color-Doppler findings with the results of US-guided fine needle aspiration biopsy and of pathologic staging of resected carcinomas to establish the relative importance of US features as risk factors of malignancy and a cost-effective management of nonpalpable thyroid nodules.
Journal ArticleDOI
New Sonographic Criteria for Recommending Fine-Needle Aspiration Biopsy of Nonpalpable Solid Nodules of the Thyroid
Eun Kyung Kim,Cheong Soo Park,Woung Youn Chung,Ki Keun Oh,Dong-Ik Kim,Jong Tae Lee,Hyung Sik Yoo +6 more
TL;DR: Considering the high level of sensitivity of the proposed sonographic classification, fine-needle aspiration biopsy should be performed on thyroid nodules classified as positive, regardless of palpability.
Journal ArticleDOI
Occult papillary carcinoma of the thyroid. A “normal” finding in finland. A systematic autopsy study
TL;DR: According to the study, OPC can be regarded as a normal finding which should not be treated when incidentally found and in order to avoid unnecessary operations it is suggested that incidentally found small OPCs were called occult papillary tumor instead of carcinoma.
Journal ArticleDOI
Thyroid Incidentalomas: Prevalence by Palpation and Ultrasonography
TL;DR: The data indicate that thyroid abnormalities are very common incidental findings, emphasizing the need for a conservative approach when such lesions are encountered incidentally.
Journal ArticleDOI
Occult Papillary Carcinoma of the Thyroid
TL;DR: Long-term follow-up showed that all patients were alive and without disease or were dead without proof of thyroid-related disease and occult papillary thyroid carcinoma with or without nodal metastasis is a nonlethal and curable disease when treated by conservative surgical means.
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