Journal ArticleDOI
Risk for Malignancy of Thyroid Nodules as Assessed by Sonographic Criteria The Need for Biopsy
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TLDR
This study indicates that the presence of intrinsic microcalcification is the only statistically reliable criterion on which to base increased suspicion for malignancy in thyroid nodules, particularly if calcifications have a snowstorm appearance on sonography.Abstract:
Objective. To correlate sonographic and color Doppler characteristics of thyroid nodules with the results of sonographically guided fine-needle aspiration biopsy to establish the relative importance of these features in predicting risk for malignancy. Methods. We retrospectively analyzed the sonographic features of 34 malignant and 36 benign thyroid nodules with respect to size, echogenicity, echo structure, shape, border, calcification, and internal vascularity. Individual features and combinations of features were analyzed for their correlation with benign or malignant disease. A comparative analysis of several authors' previously proposed methods for distinguishing between benign and malignant nodules using sonographic criteria was also performed to determine their sensitivity and specificity in predicting nodule disease within our study data. Results. Nodule size ranged from 0.8 to 4.6 cm in greatest dimension (mean, 1.96 cm; SD, 0.877 cm). The prevalence of malignancy in our study population was estimated to be nearly 5.33%. Intragroup comparison of sonographic features among benign and malignant nodules resulted in identification of intrinsic calcification as the only statistically significant predictor of malignancy (35.3% sensitive and 94.4% specific; P <.005). Presence of a "snowstorm" pattern of calcification was 100% specific for malignancy. Echogenicity, echo structure, shape, border classification, and grade of internal vascularity did not show any significant difference between benign and malignant nodules in this study. Various combinations of features previously suggested to be significant predictors of malignancy were also analyzed and shown to have very little sensitivity or specificity in predicting benign or malignant disease among nodules in our study population. Conclusions. This study indicates that the presence of intrinsic microcalcification is the only statistically reliable criterion on which to base increased suspicion for malignancy in thyroid nodules. Our results indicate the need for biopsy in determining further workup. All nodules that show the presence of intrinsic microcalcification should undergo biopsy, particularly if calcifications have a snowstorm appearance on sonography.read more
Citations
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Journal ArticleDOI
Spectral power Doppler ultrasound parameters: are they really significant?
TL;DR: There is a need for studies with larger patient populations that will eliminate the limitations mentioned above to evaluate the role of duplex PDUS in the diagnosis of malignant thyroid nodules and report that RI and PI values are significantly higher in nodules with malignancy.
Journal ArticleDOI
Strain Imaging in the Evaluation of Thyroid Nodules: The Associated Factors Leading to Misdiagnosis
TL;DR: In this paper, the authors analyzed which imaging characteristics may contribute to misdiagnosis of benign and malignant thyroid nodules (TNs) through strain imaging (SI), and applied binary logistic regression analysis to select independent variables for incorrect SI results.
Journal Article
Evaluation of Thyroid Nodule by Ultrasonography (USG Thyroid): Our Experience
Baba Aijaz Khaliq,Kiran Bala,Nadhia Bhagat,Omar Sharief Kirmani,Baba Iqbal Khaliq,Sajad Majid Qazi,Qurat Ul Ain Batool +6 more
TL;DR: USG thyroid as a diagnostic modality alone in evaluation of thyroid nodule has high sensitivity and specificity in diagnosing both benign and malignant thyroid lesions in this study.
Journal ArticleDOI
Preoperative and pathological predictive factors of central lymph node metastasis in papillary thyroid microcarcinoma
TL;DR: Wang et al. as mentioned in this paper identified clinical and pathological markers of CLNM in persons with clinical lymph node-negative papillary thyroid microcarcinoma (PTMC) from 804 PTMC clinically negative patients who were receiving thyroid surgery.
Book ChapterDOI
Thyroid and Parathyroid Neoplasms
TL;DR: X-rays of the neck, the chest or barium swallows can give hints mainly regarding thyroid disease, such as narrowing of tracheal, hypopharyngeal or oesophageal lumen, their shifting away from the midline, and coarse calcifications.
References
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Journal ArticleDOI
Risk of malignancy in nonpalpable thyroid nodules: predictive value of ultrasound and color-Doppler features.
Enrico Papini,Rinaldo Guglielmi,Antonio Bianchini,Anna Crescenzi,Silvia Taccogna,Francesco Nardi,Claudio Panunzi,R. Rinaldi,Vincenzo Toscano,Claudio Maurizio Pacella +9 more
TL;DR: The aim of the study was to correlate the sonographic and color-Doppler findings with the results of US-guided fine needle aspiration biopsy and of pathologic staging of resected carcinomas to establish the relative importance of US features as risk factors of malignancy and a cost-effective management of nonpalpable thyroid nodules.
Journal ArticleDOI
New Sonographic Criteria for Recommending Fine-Needle Aspiration Biopsy of Nonpalpable Solid Nodules of the Thyroid
Eun Kyung Kim,Cheong Soo Park,Woung Youn Chung,Ki Keun Oh,Dong-Ik Kim,Jong Tae Lee,Hyung Sik Yoo +6 more
TL;DR: Considering the high level of sensitivity of the proposed sonographic classification, fine-needle aspiration biopsy should be performed on thyroid nodules classified as positive, regardless of palpability.
Journal ArticleDOI
Occult papillary carcinoma of the thyroid. A “normal” finding in finland. A systematic autopsy study
TL;DR: According to the study, OPC can be regarded as a normal finding which should not be treated when incidentally found and in order to avoid unnecessary operations it is suggested that incidentally found small OPCs were called occult papillary tumor instead of carcinoma.
Journal ArticleDOI
Thyroid Incidentalomas: Prevalence by Palpation and Ultrasonography
TL;DR: The data indicate that thyroid abnormalities are very common incidental findings, emphasizing the need for a conservative approach when such lesions are encountered incidentally.
Journal ArticleDOI
Occult Papillary Carcinoma of the Thyroid
TL;DR: Long-term follow-up showed that all patients were alive and without disease or were dead without proof of thyroid-related disease and occult papillary thyroid carcinoma with or without nodal metastasis is a nonlethal and curable disease when treated by conservative surgical means.
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