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Journal ArticleDOI

Silver nanoparticles: A new view on mechanistic aspects on antimicrobial activity

TLDR
This overview incorporates a retrospective of previous reviews published from 2007 to 2013 and recent original contributions on the progress of research on antimicrobial mechanisms to summarize the current knowledge in the field of antibacterial activity of silver nanoparticles.
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This article is published in Nanomedicine: Nanotechnology, Biology and Medicine.The article was published on 2016-04-01. It has received 1055 citations till now. The article focuses on the topics: Silver nanoparticle.

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Citations
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Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

TL;DR: This review focused on the latest data regarding the biomedical use of AgNP-based nanostructures, including aspects related to their potential toxicity, unique physiochemical properties, and biofunctional behaviors, discussing herein the intrinsic anti-inflammatory, antibacterial, antiviral, and antifungal activities of silver-based Nanostructure.
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Green synthesis of silver nanoparticles: biomolecule-nanoparticle organizations targeting antimicrobial activity

TL;DR: The recent advances in green synthesis of silver nanoparticles, their application as antimicrobial agents and mechanism of antimicrobial mode of action are discussed.
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Potential antibacterial mechanism of silver nanoparticles and the optimization of orthopedic implants by advanced modification technologies.

TL;DR: The potential antibacterial mechanisms ofAgNPs are analyzed, and the influences of AgNPs on osteogenic-related cells, including cellular adhesion, proliferation, and differentiation, were discussed.
Journal ArticleDOI

Antibacterial Activity of Silver Nanoparticles: Structural Effects

TL;DR: This review illustrates the antibacterial mechanisms of silver nanoparticles and further elucidates how different structural factors including surface chemistry, size, and shape, impact their antibacterial activities, which are expected to promote the future development of more potent silver nanoparticle‐based antibacterial agents.
Journal ArticleDOI

Nano-Strategies to Fight Multidrug Resistant Bacteria-"A Battle of the Titans".

TL;DR: The use of nanoparticles still presents a challenge to therapy and much more research is needed in order to overcome this, so the current research on nanoparticles and other nanomaterials are summarized.
References
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Journal ArticleDOI

Oxidative stress-dependent toxicity of silver nanoparticles in human hepatoma cells

TL;DR: The findings suggest that AgNP cytotoxicity is primarily the result of oxidative stress and is independent of the toxicity of Ag(+) ions.
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Chemiosmotic Mechanism of Antimicrobial Activity of Ag+ in Vibrio cholerae

TL;DR: It is shown that low concentrations of Ag+ induce a massive proton leakage through the Vibrio cholerae membrane, which results in complete deenergization and, with a high degree of probability, cell death.
Journal ArticleDOI

Interaction of Silver(I) Ions with the Respiratory Chain of Escherichia coli: An Electrochemical and Scanning Electrochemical Microscopy Study of the Antimicrobial Mechanism of Micromolar Ag+†

TL;DR: Electrochemical techniques were used to study the behavior of Escherichia coli on the addition of
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The increasing use of silver-based products as antimicrobial agents: a useful development or a cause for concern?

TL;DR: The clinical incidence of silver resistance remains low, and emergence of resistance can be minimized if the level of silver ions released from products is high and the bactericidal activity rapid.
Journal ArticleDOI

In vitro toxicity of silver nanoparticles at noncytotoxic doses to HepG2 human hepatoma cells.

TL;DR: In vitro toxicity of Ag-NPs at noncytotoxic doses in human hepatoma cell line, HepG2, is evaluated and it is concluded that both "nanosized particle of Ag" as well as "ionic Ag+" contribute to the toxic effects of Ag.
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What is the Antimicrobial mechanism of action of silver nanoparticles?

The exact mechanism of action of silver nanoparticles as antimicrobial agents is still not completely known.