Journal ArticleDOI
Solid lipid nanoparticles (SLN)--based hydrogels as potential carriers for oral transmucosal delivery of risperidone: preparation and characterization studies.
Ana Catarina Silva,Ana Catarina Silva,Maria Helena Amaral,E. González-Mira,Delfim Santos,Domingos Ferreira +5 more
Reads0
Chats0
TLDR
Two different solid lipid nanoparticles (SLN)-based hydrogels (HGs) formulations were developed as potential mucoadhesive systems for risperidone (RISP) oral transmucosal delivery, and in vitro drug release studies revealed a more pronounced RISP release after SLN hydrogel entrapment, when compared to the dispersions alone.About:
This article is published in Colloids and Surfaces B: Biointerfaces.The article was published on 2012-05-01. It has received 86 citations till now. The article focuses on the topics: Solid lipid nanoparticle & Drug carrier.read more
Citations
More filters
Journal ArticleDOI
Formulations based on solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) for cutaneous use: A review
TL;DR: Despite the cutaneous use of SLN and NLC has been proposed for both local and transdermal delivery, the reported studies show promising results only for local application, so more research is required to better understanding the interaction mechanisms of lipid nanoparticles with skin lipids.
Journal ArticleDOI
Recent Advances in Edible Polymer Based Hydrogels as a Sustainable Alternative to Conventional Polymers.
Akbar Ali,Shakeel Ahmed +1 more
TL;DR: The application of edible polymer hydrogels covers many areas including the food industry, agricultural applications, drug delivery to tissue engineering in the biomedical field and provide more safe and attractive products in the pharmaceutical, agricultural, and environmental fields, etc.
Journal ArticleDOI
Nano-drug delivery systems in wound treatment and skin regeneration
TL;DR: This review summarized and discussed the current nano-drug delivery systems holding pivotal potential for wound healing and skin regeneration, with a special emphasis on liposomes, polymeric nanoparticles, inorganic nanoparticles; nanofibrous structures and nanohydrogel.
Journal ArticleDOI
Miconazole-loaded nanostructured lipid carriers (NLC) for local delivery to the oral mucosa: improving antifungal activity.
Alves Mendes,Ana Catarina Silva,José A. M. Catita,Fátima Cerqueira,Carla Gabriel,Carla Martins Lopes +5 more
TL;DR: It was demonstrated that the encapsulation of miconazole in NLC allows for obtaining the same therapeutic effect of a commercial oral gel formulation, using a 17-fold lower dose of miconsazole.
Journal ArticleDOI
Electron Microscopy of Pharmaceutical Systems
TL;DR: This review provides an overview of pharmaceutical systems of interest in current research and strategies for their successful electron microscopic analysis, and advantages and limitations of the different methodological approaches are discussed.
References
More filters
Journal ArticleDOI
Effectiveness of Antipsychotic Drugs in Patients with Chronic Schizophrenia
Jeffrey A. Lieberman,T. Scott Stroup,Joseph P. McEvoy,Joseph P. McEvoy,Marvin S. Swartz,Robert A. Rosenheck,Diana O. Perkins,Richard S.E. Keefe,Sonia M. Davis,C.E. Davis,Barry D. Lebowitz,Joanne B. Severe,John K. Hsiao +12 more
TL;DR: Olanzapine was the most effective in terms of the rates of discontinuation, and the efficacy of the conventional antipsychotic agent perphenazine appeared similar to that of quetiapine, risperidone, and ziprasidone.
Journal ArticleDOI
Hydrogels for biomedical applications.
TL;DR: The composition and synthesis of hydrogels, the character of their absorbed water, and permeation of solutes within their swollen matrices are reviewed to identify the most important properties relevant to their biomedical applications.
Journal ArticleDOI
Modeling and comparison of dissolution profiles.
TL;DR: Drug dissolution from solid dosage forms has been described by kinetic models in which the dissolved amount of drug (Q) is a function of the test time, t or Q=f(t).
Journal ArticleDOI
A simple equation for description of solute release II. Fickian and anomalous release from swellable devices
TL;DR: In this paper, an exponential relation M t /M ∞ = kt n may be used to describe the Fickian and non-Fickian release behavior of release systems which are prepared by incorporation of a drug in a hydrophilic, initially glassy polymer.
Journal ArticleDOI
A simple equation for description of solute release I. Fickian and non-fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs
TL;DR: In this paper, a simple exponential relation Mt/M∞ = ktn is introduced to describe the general solute release behavior of controlled release polymeric devices, where Mt is the fractional release, t is the release time, k is a constant, and n is the diffusional exponent characteristic of the release mechanism.
Related Papers (5)
Solid lipid nanoparticles: Production, characterization and applications
W. Mehnert,Karsten Mäder +1 more