State-of-the-art materials for ultrasound-triggered drug delivery.
Shashank R. Sirsi,Mark A. Borden +1 more
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TLDR
The mechanisms of interaction between drug carriers and ultrasound waves, including cavitation, streaming and hyperthermia, are described and how those interactions can promote drug release and tissue uptake are described.About:
This article is published in Advanced Drug Delivery Reviews.The article was published on 2014-06-15 and is currently open access. It has received 345 citations till now. The article focuses on the topics: Drug carrier & Targeted drug delivery.read more
Citations
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Engineered Nanoparticles for Drug Delivery in Cancer Therapy
TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
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Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
TL;DR: This review focuses on various potential applications of supramolecular hydrogels as molecular biomaterials, classified by their applications in cell cultures, tissue engineering, cell behavior, imaging, and unique applications of hydrogelators.
Journal ArticleDOI
Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems
Mahdi Karimi,Amir Ghasemi,Parham Sahandi Zangabad,Reza Rahighi,S. Masoud Moosavi Basri,S. Masoud Moosavi Basri,Hamed Mirshekari,Mandana Amiri,Z. Shafaei Pishabad,A. Aslani,Mahnaz Bozorgomid,Deepanjan Ghosh,Ali Beyzavi,A. Vaseghi,Amir Reza Aref,L. Haghani,Sajad Bahrami,Michael R. Hamblin,Michael R. Hamblin +18 more
TL;DR: This review highlights the recent advances of smart MNPs categorized according to their activation stimulus (physical, chemical, or biological) and looks forward to future pharmaceutical applications.
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Micro/Nanoparticle-Augmented Sonodynamic Therapy (SDT): Breaking the Depth Shallow of Photoactivation.
TL;DR: It is highly expected that micro/nanoparticle‐augmented SDT will be quickly developed as a new and efficient therapeutic modality which will find practical applications in cancer treatment and fundamental disciplines regarding materials science, chemistry, medicine and nanotechnology will be advanced.
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Polymer-Grafted Mesoporous Silica Nanoparticles as Ultrasound-Responsive Drug Carriers
TL;DR: This work demonstrates that doxorubicin-loaded hybrid MSNs can be triggered by remote stimuli, which is of capital importance for future applications in drug delivery and cancer therapy.
References
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Liposomal drug delivery systems: from concept to clinical applications.
TL;DR: Lipidic nanoparticles are the first nanomedicine delivery system to make the transition from concept to clinical application, and they are now an established technology platform with considerable clinical acceptance.
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The EPR effect: Unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect.
TL;DR: Molecular mechanisms of factors related to the EPR effect, the unique anatomy of tumor vessels, limitations and techniques to avoid such limitations, augmenting tumor drug delivery, and experimental and clinical findings are discussed.
Book
The Acoustic Bubble
TL;DR: In this article, the authors present a bibliographie (a la fin de chaque chapitre), and index reference record created on 2004-09-07, modified on 2016-08-08
Journal Article
A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model.
TL;DR: A new lipid formulation containing doxorubicin that has been optimized for both mild hyperthermic temperatures and rapid release times is described, found to be significantly more effective than free drug or current liposome formulations at reducing tumor growth in a human squamous cell carcinoma xenograft line.
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Ultrasonic Drug Delivery – A General Review
TL;DR: There remains a need to better understand the physics of cavitation of microbubbles and the impact that such cavitation has on cells and drug-carrying vesicle and makes cell membranes and capillaries more permeable to drugs.