Journal ArticleDOI
Stress hormones: Their interaction and regulation.
Julius Axelrod,Terry Reisine +1 more
Reads0
Chats0
TLDR
Together these agents appear to determine the complex physiologic responses to a variety of stressors.Abstract:
Stress stimulates several adaptive hormonal responses. Prominent among these responses are the secretion of catecholamines from the adrenal medulla, corticosteroids from the adrenal cortex, and adrenocorticotropin from the anterior pituitary. A number of complex interactions are involved in the regulation of these hormones. Glucocorticoids regulate catecholamine biosynthesis in the adrenal medulla and catecholamines stimulate adrenocorticotropin release from the anterior pituitary. In addition, other hormones, including corticotropin-releasing factor, vasoactive intestinal peptide, and arginine vasopressin stimulate while the corticosteroids and somatostatin inhibit adrenocorticotropin secretion. Together these agents appear to determine the complex physiologic responses to a variety of stressors.read more
Citations
More filters
Journal ArticleDOI
The inhibitory effect of hormones associated with stress on Na appetite of sheep.
Richard S. Weisinger,J. R. Blair-West,Peta Burns,Derek A. Denton,Michael J. McKinley,Brett S. Purcell,Wylie Vale,Jean Rivier,Katsunori Sunagawa +8 more
TL;DR: The inhibition of Na intake by urocortin occurred despite its stimulation of ACTH release and the subsequent increase in peripheral level of cortisol, indicating it would appear that hormones associated with stress have both excitatory and inhibitory influences on Na intake.
Journal ArticleDOI
The deprivation syndrome is the driving force of phylogeny, ontogeny and oncogeny.
TL;DR: The conservation of transduction pathways and functional homology of effector molecules clearly bear witness that the principles of life established during prokaryotic and eukaryotic unicellular evolution, although later diversified, have been unshakably cast to persist during metazoan phylogenesis.
Journal ArticleDOI
Physiological and hormonal responses to novelty exposure in rats are mainly related to ongoing behavioral activity.
W. Beerling,Jaap M. Koolhaas,A. Ahnaou,J. A. Bouwknecht,de Sietse Boer,Peter Meerlo,Wilhelmus Drinkenburg +6 more
TL;DR: The results show that novelty exposure induced significant increases in locomotor activity, heart rate, blood pressure and plasma corticosterone together with a complete lack of sleep as compared to the undisturbed control situation.
Journal ArticleDOI
Arginine vasopressin, but not corticotropin releasing factor, is a potent stimulator of adrenocorticotropic hormone following electroconvulsive treatment
TL;DR: The present results demonstrate that AVP per se can cause a release of ACTH from the anterior pituitary and increase plasma ACTH and plasma cortisol levels after electroconvulsive treatment.
Journal ArticleDOI
Blockade of the hypothalamic-pituitary-adrenal response to stress by intraventricular injection of dexamethasone: A method for studying the stress-induced peripheral effects of glucocorticoids
Monika Fleshner,Linda R. Watkins,L.L. Lockwood,Ruth E. Grahn,G. Gerhardt,Michael J. Meaney,Mark L. Laudenslager,Steven F. Maier +7 more
TL;DR: It is hypothesized that ICV DEX reduces hypothalamic corticotropin releasing hormone (CRH) synthesis and/or release and would be especially useful for those studying the effect of pituitary-adrenal hormones on steroid sensitive peripheral targets, such as the immune system.
References
More filters
Journal ArticleDOI
Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin
TL;DR: A peptide with high potency and intrinsic activity for stimulating the secretion of corticotropin-like and β-endorphinlike immunoactivities by cultured anterior pituitary cells has been purified in this paper.
Journal ArticleDOI
A Syndrome produced by Diverse Nocuous Agents
TL;DR: If the organism is severely damaged by acute non-specific nocuous agents such as exposure to cold, surgical injury, production of spinal shock, excessive muscular exercise, or intoxications with sublethal doses of diverse drugs, a typical syndrome appears, the symptoms of which are independent of the nature of the damaging agent or the pharmacological type of the drug employed.
Journal ArticleDOI
Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine.
TL;DR: Modification of the original single isotope radioenzymatic assay of Passon and Peuler permits the direct and simultaneous analysis of norepinephrine, epinephrine and dopamine in plasma samples of 50 μl or less.