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Journal ArticleDOI

Stress hormones: Their interaction and regulation.

Julius Axelrod, +1 more
- 04 May 1984 - 
- Vol. 224, Iss: 4648, pp 452-459
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TLDR
Together these agents appear to determine the complex physiologic responses to a variety of stressors.
Abstract
Stress stimulates several adaptive hormonal responses. Prominent among these responses are the secretion of catecholamines from the adrenal medulla, corticosteroids from the adrenal cortex, and adrenocorticotropin from the anterior pituitary. A number of complex interactions are involved in the regulation of these hormones. Glucocorticoids regulate catecholamine biosynthesis in the adrenal medulla and catecholamines stimulate adrenocorticotropin release from the anterior pituitary. In addition, other hormones, including corticotropin-releasing factor, vasoactive intestinal peptide, and arginine vasopressin stimulate while the corticosteroids and somatostatin inhibit adrenocorticotropin secretion. Together these agents appear to determine the complex physiologic responses to a variety of stressors.

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Citations
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Journal ArticleDOI

Mother's timing and duration of corticosterone exposure modulate offspring size and natal dispersal in the common lizard (Lacerta vivipara).

TL;DR: The results demonstrate that while corticosterone titer may signal a mother's external and/or internal environment to her developing young, differences in the timing and duration of this endocrine signal produce offspring with specialized phenotypes that exhibit different dispersal strategies.
Journal ArticleDOI

A complex mechanism of facilitation in pituitary ACTH cells: recent single-cell studies.

TL;DR: A novel circuit of messenger pathways linked by Ca2+ is proposed as the intracellular basis for the synergistic interaction of CRH- and AVP-regulated ACTH release.
Journal ArticleDOI

Effect of chronic psychological stress on insulin release from rat isolated pancreatic islets.

TL;DR: It is concluded that chronic psychological stress could increase responsiveness of pancreatic beta cells to glucose, in vitro, and thus, low insulin levels of the stressed animals, in vivo, may be due to reason(s) other than the reduction of insulin releasing capacity of pancreatIC beta cells.
Journal ArticleDOI

Effect of Acute Stress on Taste Perception: In Relation with Baseline Anxiety Level and Body Weight

TL;DR: The results revealed that thresholds for sweet and salty tastes are modulated during stressful conditions and demonstrated a relationship between taste perception and baseline anxiety levels of healthy individuals, which may be important to understand the appetite alterations in individuals under stressful conditions.
Journal ArticleDOI

Enhancement of rat lymphocyte proliferation after prolonged exposure to stress

TL;DR: The data suggest that prolonged exposure to a stressor results in an enhancement of immune cell activity, and specifically blood and splenic lymphocyte responses to phytohemagglutinin.
References
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Journal ArticleDOI

Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin

TL;DR: A peptide with high potency and intrinsic activity for stimulating the secretion of corticotropin-like and β-endorphinlike immunoactivities by cultured anterior pituitary cells has been purified in this paper.
Journal ArticleDOI

A Syndrome produced by Diverse Nocuous Agents

Hans Selye
- 01 Jul 1936 - 
TL;DR: If the organism is severely damaged by acute non-specific nocuous agents such as exposure to cold, surgical injury, production of spinal shock, excessive muscular exercise, or intoxications with sublethal doses of diverse drugs, a typical syndrome appears, the symptoms of which are independent of the nature of the damaging agent or the pharmacological type of the drug employed.
Journal ArticleDOI

Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine.

TL;DR: Modification of the original single isotope radioenzymatic assay of Passon and Peuler permits the direct and simultaneous analysis of norepinephrine, epinephrine and dopamine in plasma samples of 50 μl or less.
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