scispace - formally typeset
Journal ArticleDOI

Stress hormones: Their interaction and regulation.

Julius Axelrod, +1 more
- 04 May 1984 - 
- Vol. 224, Iss: 4648, pp 452-459
Reads0
Chats0
TLDR
Together these agents appear to determine the complex physiologic responses to a variety of stressors.
Abstract
Stress stimulates several adaptive hormonal responses. Prominent among these responses are the secretion of catecholamines from the adrenal medulla, corticosteroids from the adrenal cortex, and adrenocorticotropin from the anterior pituitary. A number of complex interactions are involved in the regulation of these hormones. Glucocorticoids regulate catecholamine biosynthesis in the adrenal medulla and catecholamines stimulate adrenocorticotropin release from the anterior pituitary. In addition, other hormones, including corticotropin-releasing factor, vasoactive intestinal peptide, and arginine vasopressin stimulate while the corticosteroids and somatostatin inhibit adrenocorticotropin secretion. Together these agents appear to determine the complex physiologic responses to a variety of stressors.

read more

Citations
More filters
Journal ArticleDOI

Acute Hypothalamic-Pituitary-Adrenal Responses to the Stress of Treadmill Exercise. Physiologic Adaptations to Physical Training

TL;DR: It is concluded that physical conditioning is associated with a reduction in pituitary-adrenal activation in response to a given workload and Alterations of the hypothalamic-pituitary and adrenal axis consistent with mild hypercortisolism and similar to findings in depression and anorexia nervosa were found only in highly trained runners.
Journal ArticleDOI

Physiopharmacological interactions between stress hormones and central serotonergic systems

TL;DR: Some mechanisms through which the sympathetic nervous system (SNS) and the hypothalamo-pituitary-adrenal (HPA) interact with central serotonergic systems are delineated, thereby conferring to these mechanisms a key role in adaptation processes.
Journal ArticleDOI

When stress happens matters: effects of earthquake timing on stress responsivity in pregnancy.

TL;DR: As pregnancy advances, women become decreasingly sensitive to the effects of stress, and this decrease in vulnerability may reflect increasing protection of the mother and fetus from adverse influences during pregnancy.
Journal ArticleDOI

A Biosocial Model of Status in Face-to-Face Primate Groups

TL;DR: It is argued that status ranks are allocated among members of a group through face-to-face interaction and that the allocation process is similar across each primate species, including humans.
OtherDOI

Adrenocortical Responses to Stress and Their Modulation in Free‐Living Vertebrates

TL;DR: The sections in this article are: Labile (Transient) Perturbation Factors, Comparative Hormone Responses to Classical Stressors, and A Case for Glucocorticosteroids as Mediators of the Emergency Life History Stage.
References
More filters
Journal ArticleDOI

Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin

TL;DR: A peptide with high potency and intrinsic activity for stimulating the secretion of corticotropin-like and β-endorphinlike immunoactivities by cultured anterior pituitary cells has been purified in this paper.
Journal ArticleDOI

A Syndrome produced by Diverse Nocuous Agents

Hans Selye
- 01 Jul 1936 - 
TL;DR: If the organism is severely damaged by acute non-specific nocuous agents such as exposure to cold, surgical injury, production of spinal shock, excessive muscular exercise, or intoxications with sublethal doses of diverse drugs, a typical syndrome appears, the symptoms of which are independent of the nature of the damaging agent or the pharmacological type of the drug employed.
Journal ArticleDOI

Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine.

TL;DR: Modification of the original single isotope radioenzymatic assay of Passon and Peuler permits the direct and simultaneous analysis of norepinephrine, epinephrine and dopamine in plasma samples of 50 μl or less.
Related Papers (5)