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Journal ArticleDOI

Stress hormones: Their interaction and regulation.

Julius Axelrod, +1 more
- 04 May 1984 - 
- Vol. 224, Iss: 4648, pp 452-459
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TLDR
Together these agents appear to determine the complex physiologic responses to a variety of stressors.
Abstract
Stress stimulates several adaptive hormonal responses. Prominent among these responses are the secretion of catecholamines from the adrenal medulla, corticosteroids from the adrenal cortex, and adrenocorticotropin from the anterior pituitary. A number of complex interactions are involved in the regulation of these hormones. Glucocorticoids regulate catecholamine biosynthesis in the adrenal medulla and catecholamines stimulate adrenocorticotropin release from the anterior pituitary. In addition, other hormones, including corticotropin-releasing factor, vasoactive intestinal peptide, and arginine vasopressin stimulate while the corticosteroids and somatostatin inhibit adrenocorticotropin secretion. Together these agents appear to determine the complex physiologic responses to a variety of stressors.

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Citations
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Journal ArticleDOI

Ecological processes and the ecology of stress: the impacts of abiotic environmental factors

TL;DR: The effects of abiotic perturbation factors and their effects on the hypothalamo-pituitary–adrenal/interrenal axis in vertebrates are focused on.
Journal ArticleDOI

Cocaine induced secretion of ACTH, beta-endorphin, and corticosterone.

TL;DR: It is demonstrated that cocaine induces the release of ACTH, beta-endorphin, and corticosterone and suggested that this response is mediated at the pituitary level.
Journal ArticleDOI

Norepinephrine and Its Metabolites in Cerebrospinal Fluid, Plasma, and Urine: Relationship to Hypothalamic-Pituitary-Adrenal Axis Function in Depression

TL;DR: Results in the depressed patients extend recent observations suggesting that dysregulation of the noradrenergic system and hypothalamic-pituitary-adrenal axis occur together in a subgroup of depressed patients.
Journal ArticleDOI

Childhood Stress and Family Environment

TL;DR: In this paper, aupres des enfants d'un village rural sur la cote orientale de Dominique montre la relation entre le stress and la composition du groupe domestique (âge, sexe, relation intergenerationnelle, nombre de personnes).
Journal ArticleDOI

Individual housing induces altered immuno-endocrine responses to psychological stress in male mice.

TL;DR: It is suggested that individual housing in itself does not change immunocompetence and corticosterone level, but does affect reactivity to a stressor, and individually housed mice showed high behavioral arousal, as well as altered immuno-endocrine parameters, when challenged with mild psychological novelty-stress.
References
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Journal ArticleDOI

Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin

TL;DR: A peptide with high potency and intrinsic activity for stimulating the secretion of corticotropin-like and β-endorphinlike immunoactivities by cultured anterior pituitary cells has been purified in this paper.
Journal ArticleDOI

A Syndrome produced by Diverse Nocuous Agents

Hans Selye
- 01 Jul 1936 - 
TL;DR: If the organism is severely damaged by acute non-specific nocuous agents such as exposure to cold, surgical injury, production of spinal shock, excessive muscular exercise, or intoxications with sublethal doses of diverse drugs, a typical syndrome appears, the symptoms of which are independent of the nature of the damaging agent or the pharmacological type of the drug employed.
Journal ArticleDOI

Simultaneous single isotope radioenzymatic assay of plasma norepinephrine, epinephrine and dopamine.

TL;DR: Modification of the original single isotope radioenzymatic assay of Passon and Peuler permits the direct and simultaneous analysis of norepinephrine, epinephrine and dopamine in plasma samples of 50 μl or less.
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