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Journal ArticleDOI

Sustained improvement in functional capacity after removal of body fluid with isolated ultrafiltration in chronic cardiac insufficiency: Failure of furosemide to provide the same result

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TLDR
In patients with congestive heart failure the set point of fluid balance is altered in spite of oral furosemide therapy; supplemental intravenous furoSemide does not shift the setpoint, at least not when combined with ACE inhibition.
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This article is published in The American Journal of Medicine.The article was published on 1994-03-01. It has received 249 citations till now. The article focuses on the topics: Furosemide & Plasma renin activity.

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Citations
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Sympathetic Nervous System Activation in Human Heart Failure: Clinical Implications of an Updated Model

TL;DR: Sympathetic activation in the setting of impaired systolic function reflects the net balance and interaction between appropriate reflex compensatory responses to impaired syStolic function and excitatory stimuli that elicit adrenergic responses in excess of homeostatic requirements.
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Role of diminished renal function in cardiovascular mortality: marker or pathogenetic factor?

TL;DR: This review provides a comprehensive analysis of the role of the kidney not only as a marker but also as a pathogenic factor in cardiorenal syndromes, whether primary heart or primary kidney disease or both are the initiators of the subsequent pathophysiological events.
References
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Value of peak exercise oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure.

TL;DR: These data suggest that cardiac transplantation can be safely deferred in ambulatory patients with severe left ventricular dysfunction and peak exercise Vo2 of more than 14 ml/min/kg.
Book

Clinical exercise testing

TL;DR: The main focus of this article will be cardiopulmonary exercise testing including indications, important measurements, salient methodological considerations, and interpretation.
Journal ArticleDOI

The Limited Reliability of Physical Signs for Estimating Hemodynamics in Chronic Heart Failure

TL;DR: The cardiovascular physical examination is used commonly as a basis for diagnosis and therapy in chronic heart failure, although the relationship between physical signs, increased ventricular filling pressure, and decreased cardiac output has not been established for this population.
Journal ArticleDOI

Activity of the sympathetic nervous system and renin-angiotensin system assessed by plasma hormone levels and their relation to hemodynamic abnormalities in congestive heart failure☆

TL;DR: It appears that the two systems are independently activated in congestive heart failure but that sympathetic stimulation may be one factor contributing to renin release, and the usefulness of plasma hormone levels is assessed.
Journal ArticleDOI

Acute Vasoconstrictor Response to Intravenous Furosemide in Patients with Chronic Congestive Heart Failure: Activation of the Neurohumoral Axis

TL;DR: Intravenous furosemide, in patients with severe chronic heart failure, is associated with acute pump dysfunction temporally related to activation of the neurohumoral axis.
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