Journal ArticleDOI
Synthesis of Imidazol-2-ylidenes by Reduction of Imidazole-2(3H)-thiones
Norbert Kuhn,Thomas Kratz +1 more
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TLDR
In this article, an improved synthesis of the title compounds was reported, and the N,N'-dialkylthioureas 1 with 3-hydroxy-2-butanone gave the imidazole-2(3H)-thiones 2 which on treatment with potassium in boiling tetrahydrofuran give the IMidazol-2ylidenes 3 in excellent yieldsAbstract:
An improved synthesis of the title compounds is reported. Reaction of the N,N'-dialkylthioureas 1 with 3-hydroxy-2-butanone gives the imidazole-2(3H)-thiones 2 which on treatment with potassium in boiling tetrahydrofuran give the imidazol-2-ylidenes 3 in excellent yieldsread more
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Synthesis of potent water-soluble tissue transglutaminase inhibitors.
Martin Griffin,Alexandre Mongeot,Russell Collighan,Robert E. Saint,Richard A. Jones,Ian G. C. Coutts,Daniel L. Rathbone +6 more
TL;DR: Dipeptide-based sulfonium peptidylmethylketones derived from 6-diazo-5-oxo-L-norleucine have been investigated as potential water-soluble inhibitors of extracellular transglUTaminase and exhibited potent activity against tissue transglutaminase.
Journal ArticleDOI
Platinum N‐Heterocyclic Carbene Nanoparticles as New and Effective Catalysts for the Selective Hydrogenation of Nitroaromatics
Patricia Lara,Andrés Suárez,Vincent Collière,Vincent Collière,Karine Philippot,Karine Philippot,Bruno Chaudret +6 more
TL;DR: In this article, the first synthesis of Pt NPs stabilized with NHC ligands and their investigation as catalysts in the chemoselective hydrogenation of nitroarenes was reported.
Journal ArticleDOI
Synthesis and Catalytic Application of Palladium Complexes with Picoline-Functionalized Benzimidazolin-2-ylidene Ligands
TL;DR: In this paper, the exact molecular structures of the benzimidazolium salts 3 and 5 and the palladium complexes 7−9 and 11 have been determined by X-ray diffraction.
Journal ArticleDOI
Synthesis, Structural Diversity, and Ligand‐Transfer Potential of (Carbene)copper(I) Complexes
TL;DR: In this article, the reaction properties of carbene-copper complexes with different N-heterocyclic carbene ligands have been investigated via in situ deprotonation and metallation.
Journal ArticleDOI
The N-heterocyclic carbene chemistry of transition-metal carbonyl clusters.
TL;DR: This critical review of the reactivity of NHCs (or their precursors) with transition-metal carbonyl clusters and on the transformations underwent by the NHC-containing species initially formed in those reactions, shows that the polynuclear character of these metallic compounds is responsible for reactivity patterns that have no parallel in the N-heterocyclic carbenes chemistry of mononuclear complexes.