Journal ArticleDOI
The association of mean glucose level and glucose variability with intensive care unit mortality in patients with severe acute pancreatitis.
TLDR
GLI was a better predictor of ICU and hospital mortality than was MGL, and together with the second 24-hour APACHE II score and the number of organ failures upon ICU admission, GLI is an independent predictor of mortality in patients with SAP.About:
This article is published in Journal of Critical Care.The article was published on 2012-04-01. It has received 28 citations till now. The article focuses on the topics: Intensive care & Risk of mortality.read more
Citations
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Glycaemic variability, infections and mortality in a medical-surgical intensive care unit
Abele Donati,Elisa Damiani,Roberta Domizi,L Botticelli,R Castagnani,Vincenzo Gabbanelli,Simonetta Nataloni,Andrea Carsetti,Claudia Scorcella,Erica Adrario,Paolo Pelaia,Jean-Charles Preiser +11 more
TL;DR: High GV is associated with higher risk of ICUCrit acquired infection and mortality and the areas under receiver operating characteristic curves were calculated to compare the discriminatory ability of GV and mean BGL for infections and mortality.
Journal ArticleDOI
Nutrition in acute pancreatitis: a critical review
Piet J. Lodewijkx,Marc G. Besselink,Ben J.M. Witteman,Nicolien J. Schepers,Hein G. Gooszen,Hjalmar C. van Santvoort,Olaf J. Bakker +6 more
TL;DR: This review provides a critical review of the available literature and concludes that enteral nutrition is superior to parenteral nutrition, although several limitations should be taken into account.
Journal ArticleDOI
Glycemic variability and outcome in critically ill.
Subhash Todi,Mahuya Bhattacharya +1 more
TL;DR: It is demonstrated that high glucose variability is associated with increased ICU mortality in a large heterogeneous cohort of ICU patients, particularly evident among patients in the euglycemic range.
Journal ArticleDOI
Poststroke glycemic variability increased recurrent cardiovascular events in diabetic patients
TL;DR: The initial glycemic variability might increase cardiovascular events in acute ischemic stroke patients with diabetes, and increased cardiovascular outcomes in highest J-index quartile were similar in both euglycemic and hyperglycemic groups.
Journal ArticleDOI
Association of multiple glycemic parameters at intensive care unit admission with mortality and clinical outcomes in critically ill patients
Priscila Bellaver,Ariell Freires Schaeffer,Diego Paluszkiewicz Dullius,Marina Verçoza Viana,Cristiane Bauermann Leitão,Tatiana Helena Rech +5 more
TL;DR: In this mixed sample of critically ill subjects, including patients with and without preexisting diabetes, Glycemic gap, glycemic variability, and SHR were associated with worse outcomes, but not with mortality.
References
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Journal ArticleDOI
Intensive Insulin Therapy in Critically Ill Patients
Greet Van den Berghe,Pieter Wouters,Frank Weekers,Charles Verwaest,Frans Bruyninckx,Miet Schetz,Dirk Vlasselaers,Patrick Ferdinande,Peter Lauwers,Roger Bouillon +9 more
TL;DR: Intensive insulin therapy to maintain blood glucose at or below 110 mg per deciliter reduces morbidity and mortality among critically ill patients in the surgical intensive care unit.
Journal ArticleDOI
Intensive versus conventional glucose control in critically ill patients.
Nice-Sugar Study Investigators,Dean R. Chittock,Steve Su,D. Blair,Denise Foster,Rinaldo Bellomo,Deborah J. Cook,Vinay Dhingra,Peter Dodek,Paul C. Hébert,William R. Henderson,Stephane Heritier,Daren K. Heyland,Colin McArthur,Ellen McDonald,Imogen Mitchell,Robyn Norton,J. Potter,Bruce G. Robinson,Juan J. Ronco +19 more
TL;DR: In this large, international, randomized trial, it was found that intensive glucose control increased mortality among adults in the ICU: a blood glucose target of 180 mg or less per deciliter resulted in lower mortality than did a target of 81 to 108 mg perDeciliter.
Journal ArticleDOI
Intensive insulin therapy and pentastarch resuscitation in severe sepsis.
Frank M. Brunkhorst,Christoph Engel,Frank Bloos,Andreas Meier-Hellmann,Max Ragaller,Norbert Weiler,Onnen Moerer,Matthias Gruendling,Michael Oppert,Stefan Grond,Derk Olthoff,Ulrich Jaschinski,Stefan John,Rolf Rossaint,Tobias Welte,Martin Schaefer,Peter M. Kern,Evelyn Kuhnt,Michael Kiehntopf,Christiane S. Hartog,Charles Natanson,Markus Loeffler,Konrad Reinhart +22 more
TL;DR: The use of intensive insulin therapy placed critically ill patients with sepsis at increased risk for serious adverse events related to hypoglycemia and HES was harmful, and its toxicity increased with accumulating doses.
Journal ArticleDOI
Activation of oxidative stress by acute glucose fluctuations compared with sustained chronic hyperglycemia in patients with type 2 diabetes.
Louis Monnier,Emilie Mas,Christine Ginet,Françoise Michel,Laetitia Villon,Jean-Paul Cristol,Claude Colette +6 more
TL;DR: Glucose fluctuations during postprandial periods and, more generally, during glucose swings exhibited a more specific triggering effect on oxidative stress than chronic sustained hyperglycemia, suggesting that interventional trials in type 2 diabetes should target not only hemoglobin A1c and mean glucose concentrations but also acute glucose swings.
Journal ArticleDOI
Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes : a systematic overview
TL;DR: Stress hyperglycaemia with myocardial infarction is associated with an increased risk of in-hospital mortality in patients with and without diabetes; the risk of congestive heart failure or cardiogenic shock is also increased in patients without diabetes.