Showing papers in "Journal of Critical Care in 2012"

TL;DR: A dearth of data describing pharmacokinetics during ECMO in critically ill adults is revealed, with most of the available data originating in neonates, and the present data indicate substantial variability and a lack of predictability in drug behavior in the presence of ECMO.

TL;DR: Use of HFNC in patients with persistent ARF was associated with significant and sustained improvement of both clinical and biologic parameters.

TL;DR: The aim of this study was to describe the current practice in measurement and documentation of vital signs and the possible usefulness of the Modified Early Warning Score (MEWS) to identify deteriorating patients on hospital wards.

TL;DR: This work points out common pitfalls in the recording and sharing of hospital acoustic parameters and points to the paucity of important economic considerations in extant studies related to noise in ICUs.

TL;DR: High-flow nasal cannula O(2) therapy appears to be an innovative and effective modality for early treatment of adults with SARI.

TL;DR: The results of this study can be of help to assist intensivists in clinical decisions and to improve characterization and risk stratification in patients with cancer with sepsis.

TL;DR: Neuromuscular electrical stimulation was associated with an increase in strength of the stimulated muscle in septic patients requiring MV and may be useful to prevent muscle weakness in this population.

TL;DR: Left ventricular end-diastolic diameter, RV-Sm, and diastolic dysfunction were able to discriminate survivors from nonsurvivors, and the combination of these parameters identified groups of very low and high risk.

TL;DR: Extracorporeal membrane oxygenation-assisted PCI for patients with AMI that is complicated by profound CS may improve the 30-day and 1-year survival rates.

TL;DR: The translational impact of computational modeling and other complex systems approaches as applied to sepsis, including in silico clinical trials, patient-specific models, and complexity-based assessments of physiology, is highlighted.

TL;DR: Patients with DKA resuscitated with PL instead of NS had faster initial resolution of metabolic acidosis and less hyperchloremia, with a transiently improved blood pressure profile and urine output.

TL;DR: Elevated SI strongly and independently forewarned of cardiovascular deterioration after emergency intubation with pre-RSI SI 0.8 or higher as the optimal threshold to identify patients at risk of PIH.

TL;DR: Atrial fibrillation is common but transient in most ICU patients, electrical cardioversion is often unsuccessful, and pharmacologic rhythm conversion is often only transiently effective, and modifiable risk factors are common among these patients.

TL;DR: Postintubation hypotension is independently associated with higher inhospital mortality and longer intensive care unit and hospital LOS, and this event occurs in almost one quarter of normotensive patients undergoing emergency intubes.

TL;DR: In this article, the effect of simulation-based education on the knowledge and skills of internal medicine residents in the medical intensive care unit (MICU) was evaluated using a 14-item checklist regarding respiratory mechanics, ventilator settings, and circulatory parameters.

TL;DR: Findings showed that factors that explain inadequate enteral nutritional intake include delayed initiation of enteral nutrition and slow advancement of infusion rate, underprescription, incomplete delivery of prescribed nutrition, and frequent interruption ofEnteral nutrition.

TL;DR: Independent risk factors were indicators of patients' severity and discharge at night, and the predictive model based on these variables showed good calibration, and should be evaluated in other ICU populations.

TL;DR: Early recovery of peripheral perfusion anticipates a successful resuscitation compared with traditional metabolic parameters in septic shock patients, and support the inclusion of serial peripheral perfusions assessment in multimodal monitoring strategies for sepsis-related circulatory dysfunction.

TL;DR: The findings of African American race, obesity, and blood product administration as independent risk factors for AKI deserve further study to elucidate underlying mechanisms.

TL;DR: Usual weaning indexes are poor predictors for extubation outcome in the overall ICU population, as measured by reintubation rate and intensive care mortality.

TL;DR: General chest ultrasound (lung and cardiac ultrasound) is a powerful diagnostic and monitoring tool reflecting an era of genuine "visual" medicine and physicians should aim to treat underlying pathologies.

TL;DR: The findings of the study suggest that the CAM-ICU is better predictor of outcome when compared with ICDSC.

TL;DR: Lactic acidosis is more common in DKA than traditionally appreciated and is not associated with increased ICU LOS or mortality, and the positive correlation of lactate with glucose raises the possibility that lactic acidotic disease may be due not only to hypoperfusion but also to altered glucose metabolism.

TL;DR: Current diagnostic practices and feeding decisions for critically ill patients should be viewed with caution until further studies determine the accuracy of bedside detection methods.

TL;DR: None of these equations accurately estimated measured REE in this group of mechanically ventilated patients, most underestimating energy needs.

TL;DR: All models showed poor calibration, while discrimination was very good for all of them in this study, so caution is warranted when using prognostic models for benchmarking.

TL;DR: Important disagreement between indirect and direct ISE sodium measurements may exist in up to 1 in 4 ICU specimens and 1 in 12 hospital-wide samples, potentially leading to misclassifications of pseudohypernatremia and pseudonormonatremia.

TL;DR: In ICU patients requiring RRT, there was marked variation in factors that influence start of RRT and RRT initiation with fewer clinical triggers was associated with lower mortality.

TL;DR: The EVLWI appears to be a good predictor of mortality in critically ill patients and was significantly higher in nonsurvivors than in survivors, according to a meta-analysis of diagnostic test studies.

TL;DR: Obtaining daily weights in ICU patients proved difficult and compliance was poor; further studies are required to establish if accurate and reproducible daily weighing of ICu patients is feasible.