The fathead minnow in aquatic toxicology: past, present and future.
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TLDR
Attributes of the fathead minnow make it an excellent model for addressing new challenges in aquatic toxicology, including identification of sensitive life-stages/endpoints for chemicals with differing modes/mechanisms of action, predicting population-level effects based on data collected from lower levels of biological organization, and exploring the emerging role of genomics in research and regulation.About:
This article is published in Aquatic Toxicology.The article was published on 2006-06-10 and is currently open access. It has received 269 citations till now. The article focuses on the topics: Aquatic toxicology & Pimephales promelas.read more
Citations
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Journal ArticleDOI
Toxicogenomics in regulatory ecotoxicology.
Gerald T. Ankley,George P. Daston,Sigmund J. Degitz,Nancy D. Denslow,Robert A. Hoke,Sean W. Kennedy,Ann L. Miracle,Edward J. Perkins,Jason Snape,Donald E. Tillitt,Charles R. Tyler,Donald J. Versteeg +11 more
TL;DR: Roles of toxicogenomics in the field of regulatory ecotoxicology are considered, current limitations in the science and practice of genomics are explored, and possible avenues to approach and resolve some of the major challenges are proposed.
Journal ArticleDOI
Endocrine Disrupting Chemicals in Fish: Developing Exposure Indicators and Predictive Models of Effects Based on Mechanism of Action
Gerald T. Ankley,David C. Bencic,Michael Breen,Timothy W. Collette,Rory B. Conolly,Nancy D. Denslow,Stephen W. Edwards,Drew R. Ekman,Natàlia Garcia-Reyero,Kathleen M. Jensen,James M. Lazorchak,Dalma Martinović,David H. Miller,Edward J. Perkins,Edward F. Orlando,Daniel L. Villeneuve,Rong-Lin Wang,Karen H. Watanabe +17 more
TL;DR: An overview and illustrative results from a large, integrated project that assesses the effects of EDCs on two small fish models, the fathead minnow (Pimephales promelas) and zebrafish, are provided.
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Polycarbonate and polystyrene nanoplastic particles act as stressors to the innate immune system of fathead minnow (Pimephales promelas)
Anne-Catherine Greven,Teresa Merk,Filiz Karagöz,Kristin Mohr,Markus Klapper,Boris Jovanović,Dušan Palić +6 more
TL;DR: The stress response of the cellular component of fish innate immune system to polystyrene and polycarbonate nanoparticles/aggregates is outlined and indicates their potential to interfere with disease resistance in fish populations.
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Linkage of biochemical responses to population‐level effects: A case study with vitellogenin in the fathead minnow (Pimephales promelas)
David H. Miller,Kathleen M. Jensen,Daniel L. Villeneuve,Michael D. Kahl,Elizabeth A. Makynen,Elizabeth J. Durhan,Gerald T. Ankley +6 more
TL;DR: Overall, the current study provides an example of how changes in a biomarker (VTG concentration) can be quantitatively translated into adverse effects at the individual and population levels.
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Dietary Exposure to 2,2´,4,4´-Tetrabromodiphenyl Ether (PBDE-47) Alters Thyroid Status and Thyroid Hormone–Regulated Gene Transcription in the Pituitary and Brain
TL;DR: The results indicate that dietary exposure to PBDE-47 alters TH signaling at multiple levels of the hypothalamic-pituitary-thyroid axis and provide evidence that TH-responsive pathways in the brain may be particularly sensitive to disruption by PBDE flame retardants.
References
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Book
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TL;DR: The most widely read reference in the water industry, Water Industry Reference as discussed by the authors, is a comprehensive reference tool for water analysis methods that covers all aspects of USEPA-approved water analysis.
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Identification of Estrogenic Chemicals in STW Effluent. 1. Chemical Fractionation and in Vitro Biological Screening
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