The Genomic Architecture and Evolutionary Fates of Supergenes.
TLDR
In this paper, the authors synthesize recent genomic work and historical models of supergene evolution, highlighting how the genomic architecture of supergenes affects their evolutionary fate, and use forward simulations to demonstrate that differences in genomic architecture affect the degeneration of super-genes.Abstract:
Supergenes are genomic regions containing sets of tightly linked loci that control multi-trait phenotypic polymorphisms under balancing selection. Recent advances in genomics have uncovered significant variation in both the genomic architecture as well as the mode of origin of supergenes across diverse organismal systems. Although the role of genomic architecture for the origin of supergenes has been much discussed, differences in the genomic architecture also subsequently affect the evolutionary trajectory of supergenes and the rate of degeneration of supergene haplotypes. In this review, we synthesize recent genomic work and historical models of supergene evolution, highlighting how the genomic architecture of supergenes affects their evolutionary fate. We discuss how recent findings on classic supergenes involved in governing ant colony social form, mimicry in butterflies, and heterostyly in flowering plants relate to theoretical expectations. Furthermore, we use forward simulations to demonstrate that differences in genomic architecture affect the degeneration of supergenes. Finally, we discuss implications of the evolution of supergene haplotypes for the long-term fate of balanced polymorphisms governed by supergenes.read more
Citations
More filters
Journal ArticleDOI
Supergene origin and maintenance in Atlantic cod
Michael Matschiner,Julia Maria Isis Barth,Ole K. Tørresen,Bastiaan Star,Helle Tessand Baalsrud,Marine S. O. Brieuc,Christophe Pampoulie,Ian Bradbury,Kjetill S. Jakobsen,Sissel Jentoft +9 more
TL;DR: This article investigated the origin and maintenance of four megabase-scale supergenes through analysis of whole-genome-sequencing data, including a new long-read-based genome assembly for a non-migratory Atlantic cod individual.
Journal ArticleDOI
Supergene origin and maintenance in Atlantic cod
Michael Matschiner,Julia Maria Isis Barth,Ole K. Tørresen,Bastiaan Star,Helle Tessand Baalsrud,Marine S. O. Brieuc,Christophe Pampoulie,Ian Bradbury,Kjetill S. Jakobsen,Sissel Jentoft +9 more
TL;DR: This paper investigated the origin and maintenance of four megabase-scale supergenes through analysis of whole-genome-sequencing data, including a new long-read-based genome assembly for a non-migratory Atlantic cod individual.
Journal ArticleDOI
A supergene underlies linked variation in color and morphology in a Holarctic songbird
Erik R. Funk,Nicholas A. Mason,Snæbjörn Pálsson,Tomáš Albrecht,Tomáš Albrecht,Jeffrey A. Johnson,Scott A. Taylor +6 more
TL;DR: Acanthis et al. as mentioned in this paper used genome sequences to investigate the genetic basis of phenotypic variation in redpoll finches and found that variation in the redpoll phenotype is broadly controlled by a ~55-Mb chromosomal inversion.
Journal ArticleDOI
Comparative Genomics Elucidates the Origin of a Supergene Controlling Floral Heteromorphism
Giacomo Potente,Étienne Léveillé-Bourret,Narjes Yousefi,Rimjhim Roy Choudhury,Barbara Keller,Seydina Issa Diop,Danny Duijsings,Walter Pirovano,Michael Lenhard,Péter Szövényi,Elena Conti +10 more
TL;DR: The present study presents the first chromosome-scale genome assembly of any heterostylous species, that of Primula veris (cowslip), and demonstrates that the S-locus evolved via multiple, asynchronous gene duplications and independent gene translocations.
Journal ArticleDOI
OUP accepted manuscript
TL;DR: In this paper , the first chromosome-scale genome assembly of any heterostylous species, that of Primula veris (cowslip), was presented, and the authors demonstrated that the S-locus evolved via multiple, asynchronous gene duplications and independent gene translocations.
References
More filters
Journal ArticleDOI
Deleterious mutation accumulation and the long-term fate of chromosomal inversions.
Emma L. Berdan,Alexandre Blanckaert,Roger K. Butlin,Roger K. Butlin,Claudia Bank,Claudia Bank +5 more
TL;DR: In this paper, the role of the allelic content in determining the long-term fate of the inversion was quantified and the authors highlighted the dynamic features of inversions by showing how the non-adaptive evolution of allele content can play a major role in the fate of inversion.
Journal ArticleDOI
A short story gets longer: recent insights into the molecular basis of heterostyly.
TL;DR: This review discusses the results from recent molecular-genetic analyses in light of the classical models on the genetics and evolution of heterostyly and suggests a scenario for the chromosomal evolution of the S locus.
Journal ArticleDOI
Genome assembly of the basket willow, Salix viminalis, reveals earliest stages of sex chromosome expansion
Pedro Almeida,Estelle Proux-Wéra,Allison M. Churcher,Lucile Soler,Jacques Dainat,Pascal Pucholt,Pascal Pucholt,Jessica Nordlund,Tom Martin,Ann-Christin Rönnberg-Wästljung,Björn Nystedt,Sofia Berlin,Judith E. Mank,Judith E. Mank +13 more
TL;DR: The data suggest that selection against recombination is a more gradual process at the earliest stages of sex chromosome formation than would be expected from an inversion and may result instead from the accumulation of transposable elements.
Journal ArticleDOI
Developmental Perspectives on Evolution of Butterfly Mimicry
TL;DR: It is believed that butterfly species that do not sequester toxins can obtain a certain level of protection from predators by sequestering in their bodies unpalatable or toxic compounds derived from the plants on which they fed when they were caterpillars.
Journal ArticleDOI
Isolation of the floral morph-related genes in heterostylous flax (Linum grandiflorum): the genetic polymorphism and the transcriptional and post-transcriptional regulations of the S locus.
Koichiro Ushijima,Ryohei Nakano,Mayu Bando,Yukari Shigezane,Kazuo Ikeda,Yuko Namba,Saori Kume,Toshiyuki Kitabata,Hitoshi Mori,Yasutaka Kubo +9 more
TL;DR: A comparison of transcript and protein accumulations showed no differences in the mRNA accumulation of some thrum-specific proteins, including LgSKS1, suggesting that these are regulated by floral morph-specific post-transcriptional regulation.