The Genomic Architecture and Evolutionary Fates of Supergenes.
TLDR
In this paper, the authors synthesize recent genomic work and historical models of supergene evolution, highlighting how the genomic architecture of supergenes affects their evolutionary fate, and use forward simulations to demonstrate that differences in genomic architecture affect the degeneration of super-genes.Abstract:
Supergenes are genomic regions containing sets of tightly linked loci that control multi-trait phenotypic polymorphisms under balancing selection. Recent advances in genomics have uncovered significant variation in both the genomic architecture as well as the mode of origin of supergenes across diverse organismal systems. Although the role of genomic architecture for the origin of supergenes has been much discussed, differences in the genomic architecture also subsequently affect the evolutionary trajectory of supergenes and the rate of degeneration of supergene haplotypes. In this review, we synthesize recent genomic work and historical models of supergene evolution, highlighting how the genomic architecture of supergenes affects their evolutionary fate. We discuss how recent findings on classic supergenes involved in governing ant colony social form, mimicry in butterflies, and heterostyly in flowering plants relate to theoretical expectations. Furthermore, we use forward simulations to demonstrate that differences in genomic architecture affect the degeneration of supergenes. Finally, we discuss implications of the evolution of supergene haplotypes for the long-term fate of balanced polymorphisms governed by supergenes.read more
Citations
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Supergene origin and maintenance in Atlantic cod
Michael Matschiner,Julia Maria Isis Barth,Ole K. Tørresen,Bastiaan Star,Helle Tessand Baalsrud,Marine S. O. Brieuc,Christophe Pampoulie,Ian Bradbury,Kjetill S. Jakobsen,Sissel Jentoft +9 more
TL;DR: This article investigated the origin and maintenance of four megabase-scale supergenes through analysis of whole-genome-sequencing data, including a new long-read-based genome assembly for a non-migratory Atlantic cod individual.
Journal ArticleDOI
Supergene origin and maintenance in Atlantic cod
Michael Matschiner,Julia Maria Isis Barth,Ole K. Tørresen,Bastiaan Star,Helle Tessand Baalsrud,Marine S. O. Brieuc,Christophe Pampoulie,Ian Bradbury,Kjetill S. Jakobsen,Sissel Jentoft +9 more
TL;DR: This paper investigated the origin and maintenance of four megabase-scale supergenes through analysis of whole-genome-sequencing data, including a new long-read-based genome assembly for a non-migratory Atlantic cod individual.
Journal ArticleDOI
A supergene underlies linked variation in color and morphology in a Holarctic songbird
Erik R. Funk,Nicholas A. Mason,Snæbjörn Pálsson,Tomáš Albrecht,Tomáš Albrecht,Jeffrey A. Johnson,Scott A. Taylor +6 more
TL;DR: Acanthis et al. as mentioned in this paper used genome sequences to investigate the genetic basis of phenotypic variation in redpoll finches and found that variation in the redpoll phenotype is broadly controlled by a ~55-Mb chromosomal inversion.
Journal ArticleDOI
Comparative Genomics Elucidates the Origin of a Supergene Controlling Floral Heteromorphism
Giacomo Potente,Étienne Léveillé-Bourret,Narjes Yousefi,Rimjhim Roy Choudhury,Barbara Keller,Seydina Issa Diop,Danny Duijsings,Walter Pirovano,Michael Lenhard,Péter Szövényi,Elena Conti +10 more
TL;DR: The present study presents the first chromosome-scale genome assembly of any heterostylous species, that of Primula veris (cowslip), and demonstrates that the S-locus evolved via multiple, asynchronous gene duplications and independent gene translocations.
Journal ArticleDOI
OUP accepted manuscript
TL;DR: In this paper , the first chromosome-scale genome assembly of any heterostylous species, that of Primula veris (cowslip), was presented, and the authors demonstrated that the S-locus evolved via multiple, asynchronous gene duplications and independent gene translocations.
References
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TL;DR: In response to the particular selection pressures associated with the maintenance of more than one mating type, this nucleus of low recombination may expand over evolutionary time, engulfing neighboring tracts bearing genes with no direct role in reproduction.
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Journal ArticleDOI
S-LOCUS EARLY FLOWERING 3 is exclusively present in the genomes of short-styled buckwheat plants that exhibit heteromorphic self-incompatibility.
Yasuo Yasui,Masashi Mori,Jotaro Aii,Tomoko Abe,Daiki Matsumoto,Shingo Sato,Yoriko Hayashi,Ohmi Ohnishi,Tatsuya Ota +8 more
TL;DR: The nonessential role of S-elf3 in the survival of individuals and the prolonged evolutionary presence only in the genomes of short-styled plants exhibiting heteromorphic SI suggests that S-ELF3 is a suitable candidate gene for the control of the short- Styled phenotype of buckwheat plants.
Journal ArticleDOI
Evolution of a supergene that regulates a trans-species social polymorphism.
Zheng Yan,Simon H. Martin,Dietrich Gotzek,Samuel V. Arsenault,Pablo Duchen,Quentin Helleu,Oksana Riba-Grognuz,Brendan G. Hunt,Nicolas Salamin,DeWayne Shoemaker,Kenneth G. Ross,Laurent Keller +11 more
TL;DR: Analysis of whole-genome sequences of males from native populations of six fire ant species shows that variation in social organization is under the control of a novel supergene haplotype (termed Sb), which evolved by sequential incorporation of three inversions spanning half of a ‘social chromosome’.