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Open AccessJournal ArticleDOI

The Hippocampal-VTA Loop: Controlling the Entry of Information into Long-Term Memory

John E. Lisman, +1 more
- 02 Jun 2005 - 
- Vol. 46, Iss: 5, pp 703-713
TLDR
The concept that the hippocampus and the midbrain dopaminergic neurons of the ventral tegmental area (VTA) form a functional loop is developed and support a model whereby the hippocampal-VTA loop regulates the entry of information into long-term memory.
About
This article is published in Neuron.The article was published on 2005-06-02 and is currently open access. It has received 1728 citations till now. The article focuses on the topics: Ventral tegmental area & Ventral pallidum.

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Citations
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Dopamine in Motivational Control: Rewarding, Aversive, and Alerting

TL;DR: It is proposed that dopamine neurons come in multiple types that are connected with distinct brain networks and have distinct roles in motivational control, and it is hypothesized that these dopaminergic pathways for value, salience, and alerting cooperate to support adaptive behavior.
Journal ArticleDOI

Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms

TL;DR: Greater appreciation of the convergence of mechanisms between stress, depression, and neuroplasticity is likely to lead to the identification of novel targets for more efficacious treatments.
Journal ArticleDOI

The role of phase synchronization in memory processes.

TL;DR: This work proposes that processes underlying working and long-term memory might interact in the medial temporal lobe and proposes that this is accomplished by neural operations involving phase–phase and phase–amplitude synchronization.
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The critical role of retrieval practice in long-term retention

TL;DR: Research is reviewed that contradicts this traditional view by demonstrating that retrieval practice is actually a powerful mnemonic enhancer, often producing large gains in long-term retention relative to repeated studying.
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Reconsidering anhedonia in depression: lessons from translational neuroscience.

TL;DR: It is suggested that a refined definition of anhedonia that distinguishes between deficits in pleasure and motivation is essential for the purposes of identifying its neurobiological substrates and introduced the term "decisionalAnhedonia" to address the influence of anhydonia on reward decision-making.
References
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Journal ArticleDOI

The medial temporal lobe

TL;DR: This analysis draws on studies of human memory impairment and animal models of memory impairment, as well as neurophysiological and neuroimaging data, to show that this system is principally concerned with memory and operates with neocortex to establish and maintain long-term memory.
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The molecular basis of CaMKII function in synaptic and behavioural memory.

TL;DR: Genetic mutations that prevent persistent activation of CaMKII block LTP, experience-dependent plasticity and behavioural memory, making this kinase a leading candidate in the search for the molecular basis of memory.
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Recognition memory: what are the roles of the perirhinal cortex and hippocampus?

TL;DR: This work focuses on the central issue in this dispute — the relative contributions of the hippocampus and the perirhinal cortex to recognition memory.
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Neuronal coding of prediction errors.

TL;DR: The coding of prediction errors may represent a basic mode of brain function that may also contribute to the processing of sensory information and the short-term control of behavior.
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Multiple reward signals in the brain

TL;DR: Recent neurophysiological studies in primates that have revealed that neurons in a limited number of brain structures carry specific signals about past and future rewards provide the first step towards an understanding of how rewards influence behaviour before they are received.
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