Journal ArticleDOI
The same but different: the biology of Theileria sporozoite entry into bovine cells
TLDR
It is suggested that the initial sporozoite binding event triggers the mobilization of intrasporozoite Ca2+ and the activation of both kinase and G-protein associated signalling processes in the parasite, which regulate the invasive capacity of the sporozoites.About:
This article is published in International Journal for Parasitology.The article was published on 1997-05-01. It has received 53 citations till now. The article focuses on the topics: Theileria & Theileria parva.read more
Citations
More filters
Journal ArticleDOI
Cytoskeleton of Apicomplexan Parasites
TL;DR: The unusual properties of actin and myosin in the Apicomplexa, the highly stereotyped microtubule populations in apicOMplexans, and a network of recently discovered novel intermediate filament-like elements in these parasites are discussed.
Journal ArticleDOI
Theileria: Intracellular protozoan parasites of wild and domestic ruminants transmitted by ixodid ticks
TL;DR: Key parameters in T. parva population dynamics are the relative importance of asymptomatic carrier cattle and animals undergoing severe disease, in transmission of the parasite to ticks, and the extent of transmission by nymphs as compared to adult ticks.
Book ChapterDOI
Microneme Proteins in Apicomplexans
TL;DR: Structural and biochemical analyses of MIC domains is providing new perspectives on how adhesion is regulated and the potentially distinct roles MICs might play in long or short range interactions during parasite attachment and entry.
Journal ArticleDOI
Inhibition of apoptosis by intracellular protozoan parasites
TL;DR: Two families of molecules, which are known for their capacity to interrupt the apoptotic program, are currently discussed in the literature and can directly interfere with molecules of the cellular death machinery.
Journal ArticleDOI
Transformation of Leukocytes by Theileria parva and T. annulata
TL;DR: The presence of the parasite in the host-cell cytoplasm modulates the state of activation of a number of signal transduction pathways, including nuclear factor-kappa B, which appear to be essential for the survival of Theileria-transformed T cells.
References
More filters
Journal ArticleDOI
Bovine T cells, B cells, and null cells are transformed by the protozoan parasite Theileria parva
Cynthia L. Baldwin,Samuel J. Black,Wendy C. Brown,Patricia A. Conrad,Bruno Goddeeris,S. W. Kinuthia,P.A. Lalor,Niall D. MacHugh,Wi Morrison,Subhash Morzaria +9 more
TL;DR: The target cells for infection and transformation by Theileria parva were investigated and it was suggested that the majority of the in vivo T. parva-transformed cells were of T-cell origin.
Journal Article
The ultrastructure of red cell invasion in malaria infections: a review.
L. H. Bannister,A. R. Dluzewski +1 more
TL;DR: The merozoite can attach reversibly to erythrocytes by its adhesive coat, then form a close, irreversible contact by its apical end, triggering secretion from membranous vesicles (rhoptries and micronemes) on to the erythropoietin membrane as mentioned in this paper.
Journal Article
Theileria annulata and T. parva infect and transform different bovine mononuclear cells.
TL;DR: The results showed that despite the many similarities between Theileria annulata and T. parva, they infected different cells of the immune system.
Journal ArticleDOI
Calcium and calmodulin antagonists inhibit human malaria parasites (Plasmodium falciparum): implications for drug design.
TL;DR: It is found by radioimmunoassay that free parasites contain CaM, and the in vitro growth of Plasmodium falciparum was sensitive to CaM antagonists, and inhibition of the parasite was proportional to known anti-CaM potency.