Journal ArticleDOI
The same but different: the biology of Theileria sporozoite entry into bovine cells
TLDR
It is suggested that the initial sporozoite binding event triggers the mobilization of intrasporozoite Ca2+ and the activation of both kinase and G-protein associated signalling processes in the parasite, which regulate the invasive capacity of the sporozoites.About:
This article is published in International Journal for Parasitology.The article was published on 1997-05-01. It has received 53 citations till now. The article focuses on the topics: Theileria & Theileria parva.read more
Citations
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Journal ArticleDOI
Theileria's Strategies and Effector Mechanisms for Host Cell Transformation: From Invasion to Immortalization.
TL;DR: In this paper, the authors explore the strategies employed by Theileria to transform leukocytes, from sporozoite invasion until immortalization of the host cell has been established, and consider putative mechanisms of protein and nutrient exchange that might occur between the parasite and the host.
Journal ArticleDOI
Theileria parva: in vitro studies on the effects of holding temperature, pH and medium on sporozoite infectivity.
TL;DR: The effects of holding temperature, pH and medium on the infectivity of Theileria parva sporozoites were investigated using an in vitro infectivity assay and sporozoite infectivity was found to be sensitive to pH variations.
Book ChapterDOI
The Toxoplasma gondii Parasitophorous Vacuole Membrane: A Multifunctional Organelle in the Infected Cell
TL;DR: This chapter reviews recent experimental insights into the biology and composition of this critical and dynamic host-parasite interface.
Dissertation
A study of the cell biology of motility in Eimeria tenella sporozoites
TL;DR: In this article, a frame-by-frame video analysis of gliding motility shows it to be an erratic non-substrate specific process and this observation was confirmed by studies of bead translocation across the cell surface occurring at an average speed of 16.9 7.6 ums-1.
Development of a novel subunit vaccine against East Coast fever based on the Theileria parva sporozoite surface protein p67
TL;DR: The research described in this thesis was aimed at the possibilities of developing a subunit vaccine against East Coast fever, based on the production of T. parva sporozoite surface major protein p67, and GFP:p67 fusion polypeptides were recognised by a monoclonal antibody, which was raised against native p67 and capable of neutralising sporozoites.
References
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Journal ArticleDOI
Models for the specific adhesion of cells to cells
TL;DR: The force required to separate two cells is shown to be greater than the expected electrical forces between cells, and of the same order of magnitude as the forces required to pull gangliosides and perhaps some integral membrane proteins out of the cell membrane.
Journal ArticleDOI
Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor.
TL;DR: It is demonstrated that free heparin and heparan sulfate can reconstitute a low affinity receptor that is, in turn, required for the high affinity binding of bFGF.
Journal ArticleDOI
Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins
TL;DR: Rolling of leukocytes on vascular endothelial cells, an early event in inflammation, can be reproduced in vitro on artificial lipid bilayers containing purified CD62, a selectin also named PADGEM and GMP-140 that is inducible on endothelial Cells.
Journal ArticleDOI
Signal transduction by lymphocyte antigen receptors
Arthur Weiss,Dan R. Littman +1 more
TL;DR: Insight gained from studies of the signaling pathways downstream of TCR and BCR stimulation is likely to contribute significantly to future understanding of mechanisms responsible for lymphocyte differentiation and for the discrimination of self from nonself in developing and mature cells.
Journal ArticleDOI
Dimerization of cell surface receptors in signal transduction
TL;DR: This review focuses on the role of dimerization of cell surface receptors in signal transduction, which appears to be a mechanism of general applicability for the regulation of signalTransduction.