Journal ArticleDOI
The same but different: the biology of Theileria sporozoite entry into bovine cells
TLDR
It is suggested that the initial sporozoite binding event triggers the mobilization of intrasporozoite Ca2+ and the activation of both kinase and G-protein associated signalling processes in the parasite, which regulate the invasive capacity of the sporozoites.About:
This article is published in International Journal for Parasitology.The article was published on 1997-05-01. It has received 53 citations till now. The article focuses on the topics: Theileria & Theileria parva.read more
Citations
More filters
Journal ArticleDOI
Cytoskeleton of Apicomplexan Parasites
TL;DR: The unusual properties of actin and myosin in the Apicomplexa, the highly stereotyped microtubule populations in apicOMplexans, and a network of recently discovered novel intermediate filament-like elements in these parasites are discussed.
Journal ArticleDOI
Theileria: Intracellular protozoan parasites of wild and domestic ruminants transmitted by ixodid ticks
TL;DR: Key parameters in T. parva population dynamics are the relative importance of asymptomatic carrier cattle and animals undergoing severe disease, in transmission of the parasite to ticks, and the extent of transmission by nymphs as compared to adult ticks.
Book ChapterDOI
Microneme Proteins in Apicomplexans
TL;DR: Structural and biochemical analyses of MIC domains is providing new perspectives on how adhesion is regulated and the potentially distinct roles MICs might play in long or short range interactions during parasite attachment and entry.
Journal ArticleDOI
Inhibition of apoptosis by intracellular protozoan parasites
TL;DR: Two families of molecules, which are known for their capacity to interrupt the apoptotic program, are currently discussed in the literature and can directly interfere with molecules of the cellular death machinery.
Journal ArticleDOI
Transformation of Leukocytes by Theileria parva and T. annulata
TL;DR: The presence of the parasite in the host-cell cytoplasm modulates the state of activation of a number of signal transduction pathways, including nuclear factor-kappa B, which appear to be essential for the survival of Theileria-transformed T cells.
References
More filters
Journal ArticleDOI
Estimated Economics of theileriosis control in Africa.
TL;DR: The input values and results presented were derived from calculations using data sources that are inadequate in content and quality, and hence should be interpreted with caution.
Journal ArticleDOI
Kinetics and pattern of organelle exocytosis during Toxoplasma gondii/host-cell interaction.
TL;DR: The vacuolar network was strongly labeled with dense-granule antibodies but not with the SAG1-specific probe, which suggests that the network is not enriched in membrane proteins, and strands extending from the parasitophorous vacuoles into the host-cell cytoplasm are labeled.
Journal ArticleDOI
Dense-granule organelles of Toxoplasma gondii: Their role in the host-parasite relationship
TL;DR: Marie-France Cesbron-Delauw reviews work on a prominent set of molecules recently characterized as components of the dense granules of Toxoplasma gondii, and discusses various aspects on their post-translational trafficking and delivery within the host cell.
Journal ArticleDOI
Cytoskeletal integrity in interphase cells requires protein phosphatase activity
John E. Eriksson,David L. Brautigan,Richard B. Vallee,Joanna B. Olmsted,Hirota Fujiki,Robert D. Goldman +5 more
TL;DR: The results indicate that there is a rapid phosphate turnover on cytoskeletal intermediate filaments and suggest that protein phosphatases are essential for the maintenance and structural integrity of two major cytOSkeletal components.
Journal ArticleDOI
Calcium ions as extracellular messengers.
TL;DR: This minireview will briefly outline the signaling function of [Ca2+10, particularly the role of[CaQsensing mechanisms within various extracellular compartments in this process], and describe the homeostatic system with two principal elements: [CaZ+],-sensing cells (e.g., parathyroid cells) and tissues that respond to either local or systemic signals.