Thermodynamics versus Kinetics in Nanosynthesis

TLDR: This Review advocates the distinction between thermodynamically and kinetically controlled scenarios, that is, whether a product forms because it is the most stable state or because the pathway leading to it has the lowest energy barrier.

Abstract: One may discover a stone tool by chance but it takes more than luck to make a car or cell phone. With the advance of nanoscience, the synthesis of increasingly sophisticated nanostructures demands a rational design and a systems approach. In this Review, we advocate the distinction between thermodynamically and kinetically controlled scenarios, that is, whether a product forms because it is the most stable state or because the pathway leading to it has the lowest energy barrier. Great endeavours have been made to describe the multiple concurrent processes in typical nanosynthesis phenomena, so that the mechanistic proposals in the literature are brought into a common framework for easy contrast and comparison.