Open AccessJournal Article
Transport and metabolism of vitamin A
TLDR
Findings on vitamin A transport from intestines to target-cell and metabolism of this fat-soluble vitamin are reviewed and possible roles of cellular retinoid-binding proteins in the process of Vitamin A transport and metabolism are reviewed.Abstract:
The present paper is a review of up-to-date findings on vitamin A transport from intestines to target-cell and metabolism of this fat-soluble vitamin. The hypotheses of possible enzymes participation in the process of etherification/hydrolysis and oxidation/reduction of vitamin A are discussed. Furthermore, possible roles of cellular retinoid-binding proteins in the process of vitamin A transport and metabolism are reviewed.read more
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Vitamin A, carotenoid and vitamin E plasma concentrations in children from Laos in relation to sex and growth failure.
TL;DR: Results show that in consideration of slightly lower levels than in venous blood, capillary blood can be used to evaluate retinol, carotenoids and α-tocopherol as biomarkers of intake or status and to evaluate the possible effect of diet on absolute and relativeCarotenoid composition in children from Europe and Laos.
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Distinct tissue distribution of metabolites of the novel glutathione-activated thiopurine prodrugs cis-6-(2-acetylvinylthio)purine and trans-6-(2-acetylvinylthio)guanine and 6-thioguanine in the mouse
TL;DR: Results show distinct patterns of metabolites depending upon the compound used and suggest that differences in metabolite levels and composition after cis-AVTP, trans-AVTG, and 6-TG treatments may partially explain the different toxicity and urinary metabolite excretion profiles previously observed.
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Impact of different protocols of nutritional supplements on the status of vitamin A in class III obese patients after Roux-en-Y gastric bypass.
TL;DR: The study showed high prevalence of VAD and among the supplementation protocols used, the one containing 10,000 IU of retinol showed the best impact, however, in cases of more severe VAD, intramuscular supplementation should be considered.
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Vitamin Supplement Use and Fatal Non-Hodgkin's Lymphoma among US Men and Women
TL;DR: Findings do not support an important relation between long-term regular use of individual supplements of vitamins A, C, and E only and multivitamins and fatal non-Hodgkin's lymphoma.
BookDOI
Pharmacoresistance in epilepsy
Luisa Rocha,Esper A. Cavalheiro +1 more
TL;DR: Pharmacoresistance in epilepsy : , PharmacoresistanceIn epilepsy :, کتابخانه دیجیتال جندی اهواز
References
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Dietary Carotenoids and Vitamins A, C, and E and Risk of Breast Cancer
Shumin M. Zhang,David J. Hunter,Michele R. Forman,Bernard Rosner,Frank E. Speizer,Graham A. Colditz,JoAnn E. Manson,Susan E. Hankinson,Walter C. Willett +8 more
TL;DR: Consumption of fruits and vegetables high in specific carotenoids and vitamins may reduce premenopausal breast cancer risk.
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International Union of Pharmacology. LX. Retinoic Acid Receptors
Pierre Germain,Pierre Germain,Pierre Chambon,Gregor Eichele,Ronald M. Evans,Mitchell A. Lazar,Mark Leid,Angel R. de Lera,Reuben Lotan,David J. Mangelsdorf,Hinrich Gronemeyer +10 more
TL;DR: This review summarizes the considerable amount of knowledge generated on retinoids, members of the nuclear hormone receptor superfamily, which regulate a wide variety of essential biological processes, such as vertebrate embryonic morphogenesis and organogenesis, cell growth arrest, differentiation and apoptosis, and homeostasis, as well as their disorders.
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Vitamins A and E: metabolism, roles and transfer to offspring.
Cathy Debier,Yvan Larondelle +1 more
TL;DR: An overview of their biological functions, metabolism and dynamics of transfer to offspring in mammals, including the biochemical aspects of their intestinal absorption, blood transport, tissue uptake, storage and catabolism is presented.
Journal ArticleDOI
Modulation of T Cell and Innate Immune Responses by Retinoic Acid
TL;DR: Retinoic acid plays a role in immune homeostasis in the steady-state but activates pathogenic T cells in conditions of inflammation.
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The vitamin A-redox hypothesis: a biochemical basis for honest signaling via carotenoid pigmentation.
TL;DR: The vitamin A–redox hypothesis is presented as a testable alternative hypothesis to the resource trade-off hypothesis for the maintenance of honesty of carotenoid pigmentation.