Travellers give wings to novel coronavirus (2019-nCoV).
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TLDR
A novel coronavirus, probably of bat origin, has caused an outbreak of severe respiratory infection in humans in Wuhan, China and has been dispersed globally by travelers.Citations
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Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak.
TL;DR: Public health measures were decisive in controlling the SARS epidemic in 2003 but whether these measures will be sufficient to control 2019-nCoV depends on addressing some unanswered questions.
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The pandemic of social media panic travels faster than the COVID-19 outbreak.
Anneliese Depoux,Anneliese Depoux,Sam Martin,Sam Martin,Emilie Karafillakis,Emilie Karafillakis,Raman Preet,Raman Preet,Annelies Wilder-Smith,Annelies Wilder-Smith,Heidi J. Larson,Heidi J. Larson +11 more
TL;DR: The creation of an interactive platform and dashboard to provide real-time alerts of rumours and concerns about coronavirus spreading globally would enable public health officials and relevant stakeholders to respond rapidly with a proactive and engaging narrative that can mitigate misinformation.
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Can we contain the COVID-19 outbreak with the same measures as for SARS?
TL;DR: COVID-19 differs from SARS in terms of infectious period, transmissibility, clinical severity, and extent of community spread, but even if traditional public health measures are not able to fully contain the outbreak of CO VID-19, they will still be effective in reducing peak incidence and global deaths.
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Going global - Travel and the 2019 novel coronavirus.
Alfonso J. Rodriguez-Morales,Kirsten MacGregor,Sanch Kanagarajah,Dipti Patel,Patricia Schlagenhauf +4 more
TL;DR: The world faces the emergence of a new pathogen, another coronavirus, with a more important outbreak in terms of number of cases and deaths, compared to SARS- coV and MERS-CoV, and the 2019-nCoV represents a big threat to global health.
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Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.
J. G. Li,Mingquan Guo,Xiaoxu Tian,Xin Wang,Xing Yang,Ping Wu,Chengrong Liu,Zixuan Xiao,Yafei Qu,Yue Yin,Chunxia Wang,Yucai Zhang,Zhaoqin Zhu,Zhenshan Liu,Chao Peng,Tongyu Zhu,Qiming Liang +16 more
TL;DR: This study presents a systematic examination of SARS-CoV-2-induced perturbation of host targets and cellular networks and reveals insights into the mechanisms by which Sars-Cov-2 triggers cytokine storms, representing a powerful resource in the pursuit for therapeutic intervention.
References
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Journal ArticleDOI
A Novel Coronavirus from Patients with Pneumonia in China, 2019.
Na Zhu,Dingyu Zhang,Wenling Wang,Xingwang Li,Bo Yang,Jingdong Song,Xiang Zhao,Baoying Huang,Weifeng Shi,Roujian Lu,Peihua Niu,Faxian Zhan,Xuejun Ma,Dayan Wang,Wenbo Xu,Wenbo Xu,Guizhen Wu,George F. Gao,Wenjie Tan +18 more
TL;DR: Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily, which is the seventh member of the family of coronaviruses that infect humans.
Journal ArticleDOI
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia.
Qun Li,Xuhua Guan,Peng Wu,Xiaoye Wang,Lei Zhou,Yeqing Tong,Ruiqi Ren,Kathy Leung,Eric H. Y. Lau,Jessica Y. Wong,Xuesen Xing,Nijuan Xiang,Yang Wu,Chao Li,Chen Qi,Dan Li,Tian Liu,Jing Zhao,Man Liu,Wenxiao Tu,Chuding Chen,Lianmei Jin,Rui Yang,Qi Wang,Suhua Zhou,Rui Wang,Hui Liu,Yingbo Luo,Yuan Liu,Ge Shao,Huan Li,Zhongfa Tao,Yang Yang,Yang Yang,Zhiqiang Deng,Boxi Liu,Zhitao Ma,Yanping Zhang,Guoqing Shi,Tommy Tsan-Yuk Lam,Joseph T. Wu,George F. Gao,George F. Gao,Benjamin J. Cowling,Bo Yang,Gabriel M. Leung,Zijian Feng +46 more
TL;DR: There is evidence that human-to-human transmission has occurred among close contacts since the middle of December 2019 and considerable efforts to reduce transmission will be required to control outbreaks if similar dynamics apply elsewhere.
Journal ArticleDOI
A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster.
Jasper Fuk-Woo Chan,Shuofeng Yuan,Kin-Hang Kok,Kelvin K. W. To,Kelvin K. W. To,Hin Chu,Jin Yang,Fanfan Xing,Jieling Liu,Cyril C. Y. Yip,Rosana W.S. Poon,Hoi Wah Tsoi,Simon Kam Fai Lo,Kwok-Hung Chan,Vincent Kwok-Man Poon,Wan Mui Chan,Jonathan Daniel Ip,Jian Piao Cai,Vincent C.C. Cheng,Honglin Chen,Honglin Chen,Christopher K.M. Hui,Kwok-Yung Yuen +22 more
TL;DR: The findings are consistent with person-to-person transmission of this novel coronavirus in hospital and family settings, and the reports of infected travellers in other geographical regions.
Journal ArticleDOI
A novel coronavirus outbreak of global health concern.
Journal ArticleDOI
Coronavirus Infections-More Than Just the Common Cold.
TL;DR: Yet another pathogenic HCoV, 2019 novel coronavirus (2019-nCoV), was recognized in Wuhan, China, and has caused serious illness and death, and the ultimate scope and effect of this outbreak is unclear at present.
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