Virology, Epidemiology, Pathogenesis, and Control of COVID-19.
Yuefei Jin,Haiyan Yang,Wangquan Ji,Weidong Wu,Shuaiyin Chen,Weiguo Zhang,Weiguo Zhang,Guangcai Duan +7 more
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TLDR
The present understanding of COVID-19 is detailed and the current state of development of measures are introduced in this review to provide a comprehensive summary to public health authorities and potential readers worldwide.Abstract:
The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Scientific advancements since the pandemic of severe acute respiratory syndrome (SARS) in 2002~2003 and Middle East respiratory syndrome (MERS) in 2012 have accelerated our understanding of the epidemiology and pathogenesis of SARS-CoV-2 and the development of therapeutics to treat viral infection. As no specific therapeutics and vaccines are available for disease control, the epidemic of COVID-19 is posing a great threat for global public health. To provide a comprehensive summary to public health authorities and potential readers worldwide, we detail the present understanding of COVID-19 and introduce the current state of development of measures in this review.read more
Citations
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Three cases of treatment with nafamostat in elderly patients with COVID-19 pneumonia who need oxygen therapy.
Sukbin Jang,Ji-Young Rhee +1 more
TL;DR: Preliminary findings show the possibility that Nafamostat can be considered to be used in elderly patients with COVID-19 pneumonia who need oxygen therapy, and the effectiveness of nafamstat should be evaluated in further studies.
Journal ArticleDOI
Monocytes and macrophages in COVID-19: Friends and foes.
Sepideh Meidaninikjeh,Nasim Sabouni,Hadi Zare Marzouni,Sajad Bengar,Ahmad Khalili,Reza Jafari +5 more
TL;DR: In this article, the authors discuss both advantageous and disadvantageous about the pathological potential of monocytes and macrophages during the infection of SARS-CoV-2 to clarify their mutual effects on immune processing as a fist line defender in the current disease.
Journal ArticleDOI
Is antibody-dependent enhancement playing a role in COVID-19 pathogenesis?
TL;DR: The pathogenesis of COVID-19 is currently believed to proceed via both directly cytotoxic and immune-mediated mechanisms, but an additional mechanism facilitating viral cell entry and subsequent damage may involve the so-called antibody-dependent enhancement (ADE).
Journal ArticleDOI
Review on 3D printing: Fight against COVID-19
Bankole I. Oladapo,Sikiru Oluwarotimi Ismail,Temitope D. Afolalu,David B. Olawade,Mohsen Zahedi +4 more
TL;DR: It was evident from this review study that AM is a proffered technology for efficient production of an improved Bio-macromolecules capable of significant COVID-19 test and personal preventive equipment (PPE) to reduce the effect of Covid-19 on the world economy.
Journal ArticleDOI
Effects of cancer on patients with COVID-19: a systematic review and meta-analysis of 63,019 participants.
TL;DR: In this paper, the authors investigated cancer incidence in patients with COVID-19 and determined whether cancer was associated with mortality among patients with COPD, and suggested that patients with underlying diseases are more vulnerable to COPD.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
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Journal ArticleDOI
A pneumonia outbreak associated with a new coronavirus of probable bat origin
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
Journal ArticleDOI
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia.
Qun Li,Xuhua Guan,Peng Wu,Xiaoye Wang,Lei Zhou,Yeqing Tong,Ruiqi Ren,Kathy Leung,Eric H. Y. Lau,Jessica Y. Wong,Xuesen Xing,Nijuan Xiang,Yang Wu,Chao Li,Chen Qi,Dan Li,Tian Liu,Jing Zhao,Man Liu,Wenxiao Tu,Chuding Chen,Lianmei Jin,Rui Yang,Qi Wang,Suhua Zhou,Rui Wang,Hui Liu,Yingbo Luo,Yuan Liu,Ge Shao,Huan Li,Zhongfa Tao,Yang Yang,Yang Yang,Zhiqiang Deng,Boxi Liu,Zhitao Ma,Yanping Zhang,Guoqing Shi,Tommy Tsan-Yuk Lam,Joseph T. Wu,George F. Gao,George F. Gao,Benjamin J. Cowling,Bo Yang,Gabriel M. Leung,Zijian Feng +46 more
TL;DR: There is evidence that human-to-human transmission has occurred among close contacts since the middle of December 2019 and considerable efforts to reduce transmission will be required to control outbreaks if similar dynamics apply elsewhere.
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
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