Virology, Epidemiology, Pathogenesis, and Control of COVID-19.
Yuefei Jin,Haiyan Yang,Wangquan Ji,Weidong Wu,Shuaiyin Chen,Weiguo Zhang,Weiguo Zhang,Guangcai Duan +7 more
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TLDR
The present understanding of COVID-19 is detailed and the current state of development of measures are introduced in this review to provide a comprehensive summary to public health authorities and potential readers worldwide.Abstract:
The outbreak of emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease (COVID-19) in China has been brought to global attention and declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Scientific advancements since the pandemic of severe acute respiratory syndrome (SARS) in 2002~2003 and Middle East respiratory syndrome (MERS) in 2012 have accelerated our understanding of the epidemiology and pathogenesis of SARS-CoV-2 and the development of therapeutics to treat viral infection. As no specific therapeutics and vaccines are available for disease control, the epidemic of COVID-19 is posing a great threat for global public health. To provide a comprehensive summary to public health authorities and potential readers worldwide, we detail the present understanding of COVID-19 and introduce the current state of development of measures in this review.read more
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Psychological Impact of the Lockdown Due to the COVID-19 Pandemic in University Workers: Factors Related to Stress, Anxiety, and Depression.
Alejandro Salazar,Jenifer Palomo-Osuna,Helena de Sola,Jose A. Moral-Munoz,María Dueñas,Inmaculada Failde +5 more
TL;DR: In this paper, the psychological impact of the coronavirus disease (COVID-19)-related lockdown in university workers, and the factors related to their levels of stress, anxiety, and depression were analyzed.
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Novel coronavirus pathogen in humans and animals: an overview on its social impact, economic impact, and potential treatments.
Rokeya Akter,Habibur Rahman,Tanima Bhattacharya,Deepak Kaushik,Vineet Mittal,Jatin Parashar,Kuldeep Kumar,Tanvir Kabir,Priti Tagde +8 more
TL;DR: In the light of thousands of infections and deaths, the World Health Organization (WHO) has declared the outbreak of coronavirus disease (COVID-19) a worldwide pandemic as discussed by the authors.
Journal ArticleDOI
Immunomodulatory effects of curcumin in systemic autoimmune diseases
Sajjad Chamani,Maryam Moossavi,Ali Naghizadeh,Mitra Abbasifard,Muhammed Majeed,Thomas P. Johnston,Amirhossein Sahebkar +6 more
TL;DR: The present narrative review sought to provide current information concerning the preclinical and clinical uses of curcumin in systemic autoimmune diseases and the immunomodulatory influence ofCurcumin on immunological reactions/processes remains mostly unknown.
Journal ArticleDOI
Dysregulated Bradykinin: Mystery in the Pathogenesis of COVID-19
Aisha Tabassum,Muhammad Iqbal,Sadia Sultan,Raghad Ali Alhuthali,Deena Ismail Alshubaili,Raghad Salah Sayyam,Lama Mohammed Abyad,Ahmed H. Qasem,Ahmad F. Arbaeen +8 more
TL;DR: This review has tried to explore the interaction between SARS-CoV-2, ACE2, bradykinin, and its metabolite des-Arg9-brady Kininin in the pathogenesis of COVID-19.
Journal ArticleDOI
A brief review on potential application of mesenchymal stem cell and secretome in combating mortality and morbidity in COVID-19 patients.
TL;DR: The current clinical findings and update on the potential use of stem cell therapy and its secretome in combating the symptoms associated with COVID-19 are presented.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
Journal ArticleDOI
Early Transmission Dynamics in Wuhan, China, of Novel Coronavirus-Infected Pneumonia.
Qun Li,Xuhua Guan,Peng Wu,Xiaoye Wang,Lei Zhou,Yeqing Tong,Ruiqi Ren,Kathy Leung,Eric H. Y. Lau,Jessica Y. Wong,Xuesen Xing,Nijuan Xiang,Yang Wu,Chao Li,Chen Qi,Dan Li,Tian Liu,Jing Zhao,Man Liu,Wenxiao Tu,Chuding Chen,Lianmei Jin,Rui Yang,Qi Wang,Suhua Zhou,Rui Wang,Hui Liu,Yingbo Luo,Yuan Liu,Ge Shao,Huan Li,Zhongfa Tao,Yang Yang,Yang Yang,Zhiqiang Deng,Boxi Liu,Zhitao Ma,Yanping Zhang,Guoqing Shi,Tommy Tsan-Yuk Lam,Joseph T. Wu,George F. Gao,George F. Gao,Benjamin J. Cowling,Bo Yang,Gabriel M. Leung,Zijian Feng +46 more
TL;DR: There is evidence that human-to-human transmission has occurred among close contacts since the middle of December 2019 and considerable efforts to reduce transmission will be required to control outbreaks if similar dynamics apply elsewhere.
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