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Water‐dispersible and soluble porous organic polymers for biomedical applications

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TLDR
This review highlights recent progress on water soluble or dispersible POPs for biomedical applications including bioimaging and biosensing, nanocarriers for drug delivery and tumor targeting, phototherapeutics, protein and gene delivery, biomacromolecule encapsulation and discrimination, and anti‐microbial activity.
Abstract
Porous organic polymers (POPs) have become an emerging class of advanced porous organic materials owing to their structural diversity and tailored functions in solid state and organic media. Creating water‐soluble and related water‐dispersible POPs is still very challenging in the research area of porous organic materials. Their porosity‐based functions with diverse topological architectures in aqueous media offer promising platforms in bio‐related fields. This review highlights recent progress on water soluble or dispersible POPs for biomedical applications including bioimaging and biosensing, nanocarriers for drug delivery and tumor targeting, phototherapeutics, protein and gene delivery, biomacromolecule encapsulation and discrimination, and anti‐microbial activity.

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References
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Journal ArticleDOI

Aggregation-induced emission

TL;DR: In this critical review, recent progress in the area ofAIE research is summarized and typical examples of AIE systems are discussed, from which their structure-property relationships are derived.
Journal ArticleDOI

Functional Supramolecular Polymers

TL;DR: The specific features of supramolecular polymers that can lead to applications in a variety of fields are reviewed, including: materials—in which processability and self-healing properties are of interest; biomedicine— in which the concerns are dynamic functionality and biodegradability; and hierarchical assembly and electronic systems—with an interest in unidirectionality of charge flow.
Journal ArticleDOI

Covalent organic frameworks (COFs): from design to applications

TL;DR: This critical review describes the state-of-the-art development in the design, synthesis, characterisation, and application of the crystalline porous COF materials.
Journal ArticleDOI

Polymers of intrinsic microporosity (PIMs): organic materials for membrane separations, heterogeneous catalysis and hydrogen storage

TL;DR: This tutorial review describes recent research directed towards the synthesis of polymer-based organic microporous materials termed Polymers of Intrinsic Microporosity (PIMs), and demonstrates the potential of PIMs for heterogeneous catalysis and hydrogen storage.
Journal ArticleDOI

Conjugated microporous polymers: design, synthesis and application

TL;DR: CMPs are unique in that they allow the complementary utilization of π-conjugated skeletons and nanopores for functional exploration and have shown great potential for challenging energy and environmental issues, as exemplified by their excellent performance in gas adsorption, heterogeneous catalysis, light emitting, light harvesting and electrical energy storage.
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What are some of the applications of porous organic polymers?

Some applications of porous organic polymers include bioimaging and biosensing, drug delivery, tumor targeting, phototherapeutics, protein and gene delivery, biomacromolecule encapsulation, and anti-microbial activity.