White matter characterization with diffusional kurtosis imaging.
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TLDR
A physically meaningful interpretation of DKI metrics in white matter regions consisting of more or less parallel aligned fiber bundles is provided by modeling the tissue as two non-exchanging compartments, the intra-axonal space and extra-AXonal space.About:
This article is published in NeuroImage.The article was published on 2011-09-01 and is currently open access. It has received 510 citations till now. The article focuses on the topics: Diffusion Kurtosis Imaging & Diffusion MRI.read more
Citations
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Journal ArticleDOI
The Human Connectome Project's neuroimaging approach
Matthew F. Glasser,Stephen M. Smith,Daniel S. Marcus,Jesper L. R. Andersson,Edward J. Auerbach,Timothy E.J. Behrens,Timothy S. Coalson,Michael P. Harms,Mark Jenkinson,Steen Moeller,Emma C. Robinson,Stamatios N. Sotiropoulos,Junqian Xu,Essa Yacoub,Kamil Ugurbil,David C. Van Essen +15 more
TL;DR: An integrated approach to data acquisition, analysis and sharing that builds upon recent advances, particularly from the Human Connectome Project (HCP), and should accelerate progress in understanding the brain in health and disease.
Journal ArticleDOI
Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation
TL;DR: In this article, the authors review, systematize and discuss models of diffusion in neuronal tissue, by putting them into an overarching physical context of coarse-graining over an increasing diffusion length scale.
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Gliomas: Diffusion Kurtosis MR Imaging in Grading
Sofie Van Cauter,Jelle Veraart,Jan Sijbers,Ronald R. Peeters,Uwe Himmelreich,Frederik De Keyzer,Stefaan Van Gool,Frank Van Calenbergh,Steven De Vleeschouwer,Wim Van Hecke,Stefan Sunaert +10 more
TL;DR: There were significant differences in kurtosis parameters between high-grade and low-grade gliomas; hence, better separation was achieved with these parameters than with conventional diffusion imaging parameters.
Journal ArticleDOI
The development of brain white matter microstructure.
TL;DR: This review focuses on studies of normative brain development from birth to early adulthood (˜25 years), and places particular emphasis on longitudinal studies and newer techniques that are being used to study microstructural white matter development.
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Multi-compartment microscopic diffusion imaging.
TL;DR: The normative values of the new biomarkers for a large cohort of healthy young adults are established, which may then support clinical diagnostics in patients, and it is shown that the microscopic diffusion indices offer direct sensitivity to pathological tissue alterations.
References
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TL;DR: An alternative approach, based on graphical techniques and simple calculations, is described, together with the relation between this analysis and the assessment of repeatability.
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Statistical methods for assessing agreement between two methods of clinical measurement
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TL;DR: TBSS aims to improve the sensitivity, objectivity and interpretability of analysis of multi-subject diffusion imaging studies by solving the question of how to align FA images from multiple subjects in a way that allows for valid conclusions to be drawn from the subsequent voxelwise analysis.
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The basis of anisotropic water diffusion in the nervous system – a technical review
TL;DR: The purpose of this review is to characterize the relationship of nuclear magnetic resonance measurements of water diffusion and its anisotropy (i.e. directional dependence) with the underlying microstructure of neural fibres.
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Estimation of the Effective Self-Diffusion Tensor from the NMR Spin Echo
TL;DR: The diagonal and off-diagonal elements of the effective self-diffusion tensor, Deff, are related to the echo intensity in an NMR spin-echo experiment.
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