X-Ray Luminescence and X-Ray Fluorescence Computed Tomography: New Molecular Imaging Modalities
TLDR
This paper reviews the development of X-ray luminescence andX-ray fluorescence CT and their relative merits and includes current problems and future research directions and the role of these modalities in future molecular imaging applications.Abstract:
X-ray luminescence and X-ray fluorescence computed tomography (CT) are two emerging technologies in X-ray imaging that provide functional and molecular imaging capability. Both emission-type tomographic imaging modalities use external X-rays to stimulate secondary emissions, either light or secondary X-rays, which are then acquired for tomographic reconstruction. These modalities surpass the limits of sensitivity in current X-ray imaging and have the potential of enabling X-ray imaging to extract molecular imaging information. These new modalities also promise to break through the spatial resolution limits of other in vivo molecular imaging modalities. This paper reviews the development of X-ray luminescence and X-ray fluorescence CT and their relative merits. The discussion includes current problems and future research directions and the role of these modalities in future molecular imaging applications.read more
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References
More filters
Journal ArticleDOI
Gold nanoparticles: assembly, supramolecular chemistry, quantum-size-related properties, and applications toward biology, catalysis, and nanotechnology.
TL;DR: A review of gold nanoparticles can be found in this article, where the most stable metal nanoparticles, called gold colloids (AuNPs), have been used for catalysis and biology applications.
Journal ArticleDOI
Toxic Potential of Materials at the Nanolevel
TL;DR: The establishment of principles and test procedures to ensure safe manufacture and use of nanomaterials in the marketplace is urgently required and achievable.
Journal ArticleDOI
Green fluorescent protein as a marker for gene expression
TL;DR: A complementary DNA for the Aequorea victoria green fluorescent protein produces a fluorescent product when expressed in prokaryotic or eukaryotic cells, which can be used to monitor gene expression and protein localization in living organisms.
Journal ArticleDOI
Maximum Likelihood Reconstruction for Emission Tomography
L. A. Shepp,Y. Vardi +1 more
TL;DR: In this paper, the authors proposed a more accurate general mathematical model for ET where an unknown emission density generates, and is to be reconstructed from, the number of counts n*(d) in each of D detector units d. Within the model, they gave an algorithm for determining an estimate? of? which maximizes the probability p(n*|?) of observing the actual detector count data n* over all possible densities?.
Journal ArticleDOI
Renal clearance of quantum dots.
Hak Soo Choi,Wenhao Liu,Preeti Misra,Eiichi Tanaka,John P. Zimmer,Binil Itty Ipe,Moungi G. Bawendi,John V. Frangioni,John V. Frangioni +8 more
TL;DR: This study has precisely defined the requirements for renal filtration and urinary excretion of inorganic, metal-containing nanoparticles and provides a foundation for the design and development of biologically targeted nanoparticles for biomedical applications.