A
Adrian M. Zelazny
Researcher at National Institutes of Health
Publications - 126
Citations - 6760
Adrian M. Zelazny is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Mycobacterium abscessus & Nontuberculous mycobacteria. The author has an hindex of 36, co-authored 115 publications receiving 5637 citations. Previous affiliations of Adrian M. Zelazny include Sheba Medical Center & United States Department of Health and Human Services.
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Journal ArticleDOI
Tracking a Hospital Outbreak of Carbapenem-Resistant Klebsiella pneumoniae with Whole-Genome Sequencing
Evan S. Snitkin,Adrian M. Zelazny,Pamela J. Thomas,Frida Stock,David K. Henderson,Tara N. Palmore,Julia A. Segre +6 more
TL;DR: Tracking a hospital outbreak of carbapenem-resistant Klebsiella pneumoniae with whole-genome sequencing revealed its origin and probable modes of transmission, and revealed the weaknesses in this medical who-done-it, informing improvements in hospital preventive measures.
Journal ArticleDOI
GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics and immunity
Michael A. Spinner,Lauren A. Sanchez,Amy P. Hsu,Pamela A. Shaw,Christa S. Zerbe,Katherine R. Calvo,Diane C. Arthur,Wenjuan Gu,Christine M. Gould,Carmen C. Brewer,Edward W. Cowen,Alexandra F. Freeman,Kenneth N. Olivier,Gulbu Uzel,Adrian M. Zelazny,Janine Daub,Christine Spalding,Reginald J. Claypool,Neelam Giri,Blanche P. Alter,Emily M. Mace,Jordan S. Orange,Jennifer Cuellar-Rodriguez,Dennis D. Hickstein,Steven M. Holland +24 more
TL;DR: GATA2 deficiency unites susceptibility to MDS/AML, immunodeficiency, pulmonary disease, and vascular/lymphatic dysfunction, and monocytopenia, B, NK, and CD4 lymphocy topenia correlated with the presence of disease.
Journal ArticleDOI
Adult-Onset Immunodeficiency in Thailand and Taiwan
Sarah K. Browne,Peter D. Burbelo,Ploenchan Chetchotisakd,Yupin Suputtamongkol,Sasisopin Kiertiburanakul,Pamela A. Shaw,Jennifer L. Kirk,Kamonwan Jutivorakool,Kamonwan Jutivorakool,Rifat Zaman,Li Ding,Amy P. Hsu,Smita Y. Patel,Kenneth N. Olivier,Viraphong Lulitanond,Piroon Mootsikapun,Siriluck Anunnatsiri,Nasikarn Angkasekwinai,Boonmee Sathapatayavongs,Po-Ren Hsueh,Chi Chang Shieh,Margaret R. Brown,Wanna Thongnoppakhun,Reginald J. Claypool,Elizabeth P. Sampaio,Elizabeth P. Sampaio,Charin Thepthai,Duangdao Waywa,Camilla Dacombe,Yona Reizes,Adrian M. Zelazny,Paul Saleeb,Lindsey B. Rosen,Allen Mo,Allen Mo,Michael J. Iadarola,Steven M. Holland +36 more
TL;DR: In this paper, Wu et al. found that autoantibodies against interferon-γ are associated with severe disseminated opportunistic infection, but their importance and prevalence are unknown.
Journal ArticleDOI
The Case for Adopting the "Species Complex" Nomenclature for the Etiologic Agents of Cryptococcosis.
Kyung J. Kwon-Chung,John E. Bennett,Brian L. Wickes,Wieland Meyer,Christina A. Cuomo,Kurt R. Wollenburg,Tihana Bicanic,Elizabeth Castañeda,Yun C. Chang,Jianghan Chen,Massimo Cogliati,Françoise Dromer,David Ellis,Scott G. Filler,Matthew C. Fisher,Thomas S. Harrison,Steven M. Holland,Shigeru Kohno,James W. Kronstad,Márcia dos Santos Lazéra,Stuart M. Levitz,Michail S. Lionakis,Robin C. May,Popchai Ngamskulrongroj,Peter G. Pappas,John R. Perfect,Volker Rickerts,Tania C. Sorrell,Thomas J. Walsh,Peter R. Williamson,Jianping Xu,Adrian M. Zelazny,Arturo Casadevall +32 more
TL;DR: In the absence of biological differences between clades and no consensus about how DNA sequence alone can delineate a species, it is recommended to use “Cryptococcus neoformans species complex” and “C. gattii speciescomplex” as a practical intermediate step, rather than creating more species.
Journal ArticleDOI
Common Severe Infections in Chronic Granulomatous Disease
Beatriz E. Marciano,Christine Spalding,Alan Fitzgerald,Daphne Mann,Tom Brown,Sharon M. Osgood,Lynne Yockey,Dirk Darnell,Lisa A. Barnhart,Janine Daub,Lisa Boris,Amy Rump,Victoria L. Anderson,Carissa Haney,Douglas B. Kuhns,Sergio D. Rosenzweig,Corin Kelly,Adrian M. Zelazny,Tamika Mason,Suk See DeRavin,Elizabeth M. Kang,John I. Gallin,Harry L. Malech,Kenneth N. Olivier,Gulbu Uzel,Alexandra F. Freeman,Theo Heller,Christa S. Zerbe,Steven M. Holland +28 more
TL;DR: Fungal infections remain a major determinant of survival in CGD, and X-linked patients generally had more severe disease, and this was generally in those with lower residual superoxide production.