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Amanda M. V. Brown
Researcher at Texas Tech University
Publications - 29
Citations - 696
Amanda M. V. Brown is an academic researcher from Texas Tech University. The author has contributed to research in topics: Genome & Wolbachia. The author has an hindex of 14, co-authored 28 publications receiving 568 citations. Previous affiliations of Amanda M. V. Brown include Oregon State University & University of British Columbia.
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Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases
Jialiang Yang,Tao Huang,Francesca Petralia,Quan Long,Bin Zhang,Carmen Argmann,Yong Zhao,Charles V. Mobbs,Eric E. Schadt,Jun Zhu,Zhidong Tu,Kristin G. Ardlie,David S. DeLuca,Ayellet V. Segrè,Timothy J. Sullivan,Taylor Young,Ellen Gelfand,Casandra A. Trowbridge,Julian Maller,Taru Tukiainen,Monkol Lek,Lucas D. Ward,Lucas D. Ward,Pouya Kheradpour,Pouya Kheradpour,Benjamin Iriarte,Yan Meng,Cameron D. Palmer,Wendy Winckler,Joel N. Hirschhorn,Manolis Kellis,Manolis Kellis,Daniel G. MacArthur,Gad Getz,Andrey A. Shablin,Gen Li,Yi-Hui Zhou,Andrew B. Nobel,Ivan Rusyn,Ivan Rusyn,Fred A. Wright,Tuuli Lappalainen,Pedro G. Ferreira,Pedro G. Ferreira,Halit Ongen,Halit Ongen,Manuel A. Rivas,Alexis Battle,Alexis Battle,Sara Mostafavi,Jean Monlong,Jean Monlong,Michael Sammeth,Marta Melé,Marta Melé,Ferran Reverter,Jakob Goldman,Daphne Koller,Roderic Guigó,Mark I. McCarthy,Emmanouil T. Dermitzakis,Emmanouil T. Dermitzakis,Eric R. Gamazon,Anuar Konkashbaev,Dan L. Nicolae,Nancy J. Cox,Timothée Flutre,Xiaoquan Wen,Matthew Stephens,Jonathan K. Pritchard,Jonathan K. Pritchard,Jonathan K. Pritchard,Luan Lin,Jun Liu,Amanda M. V. Brown,Bernadette Mestichelli,Denee Tidwell,Edmund Lo,Mike Salvatore,Saboor Shad,Jeffrey A. Thomas,John T. Lonsdale,Christopher Choi,Ellen Karasik,Kimberly Ramsey,Michael T. Moser,Barbara A. Foster,Bryan Gillard,John Syron,Johnelle Fleming,Harold Magazine,Rick Hasz,Gary Walters,Jason Bridge,Mark Miklos,Susan L. Sullivan,Laura Barker,Heather M. Traino,Magboeba Mosavel,Laura A. Siminoff,Laura A. Siminoff,Dana R. Valley,Daniel C. Rohrer,Scott Jewel,Philip A. Branton,Leslie H. Sobin,Liqun Qi,Pushpa Hariharan,Shenpei Wu,David Tabor,Charles Shive,Anna M. Smith,Stephen A. Buia,Anita H. Undale,Karna Robinson,Nancy Roche,Kimberly M. Valentino,Angela Britton,Robin Burges,Debra Bradbury,Kenneth W. Hambright,John Seleski,Greg E. Korzeniewski,Kenyon Erickson,Yvonne Marcus,Jorge Tejada,Mehran Taherian,Chunrong Lu,Barnaby E. Robles,Margaret J. Basile,Deborah C. Mash,Simona Volpi,Jeff Struewing,Gary F. Temple,Joy T. Boyer,Deborah Colantuoni,Roger Little,Susan E. Koester,Latarsha J. Carithers,Helen M. Moore,Ping Guan,Carolyn C. Compton,Sherilyn Sawyer,Joanne P. Demchok,Jimmie B. Vaught,Chana A. Rabiner,Nicole C. Lockhart +146 more
TL;DR: In this article, the aging gene expression signatures are very tissue specific and enrichment for some well-known aging components such as mitochondria biology is observed in many tissues, and different levels of cross-tissue synchronization of age-related gene expression changes are observed, and some essential tissues (e.g., heart and lung) show much stronger "co-aging" than other tissues based on principal component analysis.
Journal ArticleDOI
Pseudoloma neurophilia n. g., n. sp., a New Microsporidium from the Central Nervous System of the Zebrafish (Danio rerio)
Jennifer L Matthews,Amanda M. V. Brown,Karen D. Larison,Janell K. Bishop-Stewart,Paul Rogers,Michael L. Kent +5 more
TL;DR: The rDNA sequence of the zebrafish microsporidium can be considered a distinct genus and species, which is named Pseudoloma neurophilia n.
Journal ArticleDOI
Population genomics of a symbiont in the early stages of a pest invasion
TL;DR: Genetic analyses of allele frequency changes between 2009 and 2011 uncover signatures of both positive and negative selection and suggest that symbionts on soybeans and kudzu experience differential selection for genes related to nutrient provisioning.
Journal ArticleDOI
Genomic evidence for plant-parasitic nematodes as the earliest Wolbachia hosts
Amanda M. V. Brown,Sulochana K. Wasala,Dana K. Howe,Amy B. Peetz,Inga A. Zasada,Dee R. Denver +5 more
TL;DR: The genome of a new Wolbachia strain in the plant-parasitic nematode Pratylenchus penetrans is sequenced and analyzed, enhancing understanding of this globally pandemic endosymbiont and highlighting genetic patterns associated with host changes.
Journal ArticleDOI
Comparative Genomics of a Plant-Parasitic Nematode Endosymbiont Suggest a Role in Nutritional Symbiosis
Amanda M. V. Brown,Dana K. Howe,Sulochana K. Wasala,Amy B. Peetz,Inga A. Zasada,Dee R. Denver +5 more
TL;DR: Together, features and the location in the gut suggest that Xiphinematobacter functions as a nutritional mutualist, supplementing essential nutrients that are depleted in the nematode diet, which points to evolutionary convergence with endosymbionts found in sap-feeding insects.