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Andre E. Nel
Researcher at University of California, Los Angeles
Publications - 423
Citations - 62202
Andre E. Nel is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Biology & Paleontology. The author has an hindex of 105, co-authored 325 publications receiving 56090 citations. Previous affiliations of Andre E. Nel include Stellenbosch University & University of California, Berkeley.
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Book ChapterDOI
Applications: Nanobiosystems, Medicine, and Health
TL;DR: This work has shown that fabrication of a host of nanostructures has been coupled with advanced chemical manipulation in order to impart biological recognition and interaction capabilities and results in nanomaterials that provide performance enhancement of therapeutics, imaging agents, diagnostics, and materials for tissue engineering and for basic science applications.
Journal ArticleDOI
Evidence for involvement of glycoprotein-CD45 phosphatase in reversing glycoprotein-CD3-induced microtubule-associated protein-2 kinase activity in Jurkat T-cells
Shimon Pollack,Jeffrey A. Ledbetter,Rina Katz,Katherine Williams,Brian J. Akerley,Kymberly Franklin,Gary L. Schieven,Andre E. Nel +7 more
TL;DR: It is shown that CD45 could inhibit the induction of MAP-2K activity in intact Jurkat cells during CD3 or CD3 + CD4 stimulation, and the ability of purified CD45 phosphatase to remove tyrosine phosphates from partially purified lymphoid MAP- 2K is demonstrated.
Journal ArticleDOI
Dissolution of 2D Molybdenum Disulfide Generates Differential Toxicity among Liver Cell Types Compared to Non-Toxic 2D Boron Nitride Effects
Jiulong Li,Linda M. Guiney,Julia R. Downing,Xiang Wang,Chong Hyun Chang,Jinhong Jiang,Qi Liu,Xiangsheng Liu,Kuo-Ching Mei,Yu-Pei Liao,Tiancong Ma,Huan Meng,Mark C. Hersam,Andre E. Nel,Tian Xia +14 more
TL;DR: In this article, the toxicity of 2D boron nitride and molybdenum disulfide (MoS2) materials were compared with aggregated forms of these materials (BN-Agg and MoS2 -Agg) in liver cells.
Journal ArticleDOI
The Genetic Heterogeneity among Different Mouse Strains Impacts the Lung Injury Potential of Multiwalled Carbon Nanotubes
TL;DR: Data demonstrate that genetic background indeed plays a major role in determining the pro-fibrogenic response to MWCNTs in the lung, and a correlation between IL-1β production in BMDM and the lung fibrosis is confirmed.
Journal ArticleDOI
Evidence for LFA-1/ICAM-1 dependent stimulation of protein tyrosine phosphorylation in human B lymphoid cell lines during homotypic adhesion.
TL;DR: Results suggest that an LFA‐1‐dependent PTK pathway may play an important role in human B cell function, and patients with the leukocyte adhesion defect (LAD) exhibit humoral abnormalities.