A
Andre E. Nel
Researcher at University of California, Los Angeles
Publications - 423
Citations - 62202
Andre E. Nel is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Biology & Paleontology. The author has an hindex of 105, co-authored 325 publications receiving 56090 citations. Previous affiliations of Andre E. Nel include Stellenbosch University & University of California, Berkeley.
Papers
More filters
Journal ArticleDOI
Qualitative and quantitative studies of Gc (vitamin D-binding protein) in normal subjects and patients with periodontal disease.
Joe W. Krayer,David L. Emerson,Pascal J. Goldschmidt-Clermont,Andre E. Nel,Philip A.M. Werner,Robert M. Galbraith +5 more
TL;DR: The whole saliva of patients with periodontal disease contained concentrations of Gc which were significantly increased over those in either dentulous or edentulous control subjects, and 90% of GC in saliva from these patients was complexed with G-actin.
Nanoinformatics 2020 Roadmap
Diana de la Iglesia,Stacey L. Harper,Mark D. Hoover,Fred Klaessig,Phil Lippell,Bettye L. S. Maddux,Jeffrey Morse,Andre E. Nel,Krishna Rajan,Rebecca Reznik-Zellen,Mark T. Tuominen +10 more
TL;DR: The Nanoinformatics 2020 Roadmap as mentioned in this paper is the first broad-based community effort to articulate the comprehensive needs and goals in nano-informatic research and development efforts.
Journal ArticleDOI
Nanocarrier Co-formulation for Delivery of a TLR7 Agonist plus an Immunogenic Cell Death Stimulus Triggers Effective Pancreatic Cancer Chemo-immunotherapy.
TL;DR: A lipid bilayer-coated mesoporous silica nanoparticle (silicasome) platform for co-delivery of the TLR7/8 agonist 3M-052 and the accompanying increase in CD8+ T-cell infiltration along with a reduced number of regulatory T-cells was associated with tumor shrinkage and metastasis disappearance in subcutaneous and orthotopic KRAS-mediated pancreatic carcinoma tumor models.
Patent
Mesoporous silica nanoparticles with lipid bilayer coating for cargo delivery
TL;DR: In this article, a nanocarrier including a silica body having a surface and defining a plurality of pores that are suitable to receive molecules therein is described, which includes a lipid bilayer coating the surface, and a cargo-trapping agent within the phospholipid bilayer.
Journal ArticleDOI
Filling knowledge gaps that distinguish the safety profiles of nano versus bulk materials.
TL;DR: Research into the hazards of engineered nanomaterials has spawned the development of a new multidisciplinary science—nanotoxicology—which aims to understand the toxicological effects of these materials.