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Andre E. Nel
Researcher at University of California, Los Angeles
Publications - 423
Citations - 62202
Andre E. Nel is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Biology & Paleontology. The author has an hindex of 105, co-authored 325 publications receiving 56090 citations. Previous affiliations of Andre E. Nel include Stellenbosch University & University of California, Berkeley.
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Journal ArticleDOI
Antigen- and Epitope-Delivering Nanoparticles Targeting Liver Induce Comparable Immunotolerance in Allergic Airway Disease and Anaphylaxis as Nanoparticle-Delivering Pharmaceuticals
Qi Liu,Xiang Wang,Xiangsheng Liu,Yu-Pei Liao,Chong Hyun Chang,Kuo-Ching Mei,Jinhong Jiang,Shannon Tseng,Grant Gochman,Marissa Huang,Zoe Thatcher,Jiulong Li,Sean D. Allen,Luke Lucido,Tian Xia,Andre E. Nel +15 more
TL;DR: The targeting of natural tolerogenic liver sinusoidal endothelial cells (LSEC) by nanoparticles (NPs), decorated with a stabilin receptor ligand, is capable of generating regulatory T-cells (Tregs).
Journal ArticleDOI
Identification of a major endogenous substrate for phospholipid/Ca2+-dependent kinase in pancreatic acini as Gc (vitamin D-binding protein)
Marie W. Wooten,Andre E. Nel,Pascal J. Goldschmidt-Clermont,Robert M. Galbraith,Robert W. Wrenn +4 more
TL;DR: Findings indicate the potential usefulness of Gc as a defined substrate for further studies of the biological role of C‐kinase activity in pancreatic acini and possibly in other cells.
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Toxicological Profiling of Highly Purified Single-Walled Carbon Nanotubes with Different Lengths in the Rodent Lung and Escherichia Coli.
Xiang Wang,Jae-Hyeok Lee,Ruibin Li,Yu-Pei Liao,Joohoon Kang,Chong Hyun Chang,Linda M. Guiney,Vahid Mirshafiee,Linjiang Li,Jianqin Lu,Tian Xia,Mark C. Hersam,Andre E. Nel +12 more
TL;DR: The data demonstrate that over the length scale tested, the biological response to highly purified SWCNTs is dependent on the complexity of the nano/bio interface.
Journal ArticleDOI
Dithranol mediates pro-oxidative inhibition of polymorphonuclear leukocyte migration and lymphocyte proliferation.
Ronald Anderson,Pauline T. Lukey,U. Dippenaar,H. A. Eftychis,G. H. Findlay,Marie W. Wooten,Andre E. Nel +6 more
TL;DR: It is demonstrated that dithranol, but not its auto‐oxidation products, activates PKC which in turn initiates the generation of reactive oxidants by PMNL.
Journal ArticleDOI
CD40-mediated p38 mitogen-activated protein kinase activation is required for immunoglobulin class switch recombination to IgE.
TL;DR: In this article, CD40 activation of p38 MAPK correlated with CD40-dependent Sμ-Sϵ recombination, as determined by using a digestion circularization PCR assay.