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Andre E. Nel
Researcher at University of California, Los Angeles
Publications - 423
Citations - 62202
Andre E. Nel is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Biology & Paleontology. The author has an hindex of 105, co-authored 325 publications receiving 56090 citations. Previous affiliations of Andre E. Nel include Stellenbosch University & University of California, Berkeley.
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Journal ArticleDOI
The Crystallinity and Aspect Ratio of Cellulose Nanomaterials Determine Their Pro-Inflammatory and Immune Adjuvant Effects In Vitro and In Vivo.
Xiang Wang,Chong Hyun Chang,Jinhong Jiang,Qi Liu,Yu-Pei Liao,Jianqin Lu,Linjiang Li,Xiangsheng Liu,Joshua Kim,Ayman Ahmed,Andre E. Nel,Tian Xia +11 more
TL;DR: The data demonstrate the importance of length scale, crystallinity, and surface reactivity in shaping the innate immune response to nanocellulose.
Journal ArticleDOI
The role of phase II antioxidant enzymes in protecting memory T cells from spontaneous apoptosis in young and old mice.
Hyon-Jeen Kim,Andre E. Nel +1 more
TL;DR: This study demonstrates increased glutathione production and phase II enzyme expression and the accompanying increase in intracellular thiol levels, which combine to protect memory T cells against oxidative stress, mitochondrial dysfunction, and cell death.
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Latex Antigens: Identification and Use in Clinical and Experimental Studies, Including Crossreactivity with Food and Pollen Allergens
TL;DR: The identification of latex allergens is paving the way for studying the molecular basis of immunoreactivity to these proteins, including crossreactivity with food and other allergens, according to the allergen profile of natural rubber latex.
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Developmental regulation of pp44/46, tyrosine-phosphorylated proteins associated with tyrosine/serine kinase activity in Trypanosoma brucei
TL;DR: The data indicate that the prominent tyrosine-phosphorylated proteins induced upon differentiation are either themselves protein kinases or that they are associated withprotein kinases.
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Toxicological Profiling of Highly Purified Metallic and Semiconducting Single-Walled Carbon Nanotubes in the Rodent Lung and E. coli
Xiang Wang,Nikhita D. Mansukhani,Linda M. Guiney,Jae-Hyeok Lee,Ruibin Li,Bingbing Sun,Yu-Pei Liao,Chong Hyun Chang,Zhaoxia Ji,Tian Xia,Mark C. Hersam,Andre E. Nel +11 more
TL;DR: In vitro screening showed that both tube variants trigger similar amounts of interleukin 1β and transforming growth factor production in THP-1 and BEAS-2B cells, without cytotoxicity, and oropharyngeal aspiration confirmed that both SWCNT variants induce comparable fibrotic effects in the lung.