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Maximilien Tailler

Researcher at French Institute of Health and Medical Research

Publications -  18
Citations -  2735

Maximilien Tailler is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Myeloid leukemia & Tyrosine kinase. The author has an hindex of 16, co-authored 18 publications receiving 2394 citations. Previous affiliations of Maximilien Tailler include University of Paris-Sud & Institut Gustave Roussy.

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Journal ArticleDOI

Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice.

Mickaël Michaud, +40 more
- 16 Dec 2011 - 
TL;DR: It is demonstrated that autophagy, which is often disabled in cancer, is dispensable for chemotherapy-induced cell death but required for its immunogenicity, and increased extracellular ATP concentrations improve the efficacy of antineoplastic chemotherapies when Autophagy is disabled.
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An immunosurveillance mechanism controls cancer cell ploidy

Laura Senovilla, +88 more
- 28 Sep 2012 - 
TL;DR: It is reported that hyperploid cancer cells become immunogenic because of a constitutive endoplasmic reticulum stress response resulting in the aberrant cell surface exposure of calreticulin, which causes recognition of cancer cells in mice by the host immune system.
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Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress

Isabelle Martins, +34 more
- 10 Mar 2011 - 
TL;DR: The combination of ER stress inducers (such as THAPS or tunicamycin) and CDDP effectively induced the translocation of CRT to the plasma membrane, as well as immunogenic cell death, although ER stress or CDDP alone was insufficient to induce CRT exposure and immunogeniccell death.
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The IKK complex contributes to the induction of autophagy

Alfredo Criollo, +47 more
- 03 Feb 2010 - 
TL;DR: It is shown that multiple inducers of autophagy, including nutrient depletion, trigger the activation of the IKK (IκB kinase) complex that is best known for its essential role in theactivation of the transcription factor NF‐κB by stress.
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Prognostic impact of vitamin B6 metabolism in lung cancer.

Lorenzo Galluzzi, +135 more
- 30 Aug 2012 - 
TL;DR: Results indicate that PDXK expression levels constitute a biomarker for risk stratification among patients with NSCLC, in line with a general role of vitamin B6 in stress responses.