Alp Üçok

TL;DR: The authors present consensus guidelines that operationalize criteria for determining and reporting treatment resistance, adequate treatment, and treatment response, providing a benchmark for research and clinical translation in schizophrenia.

TL;DR: In this article , a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and 243,649 control individuals was conducted, and the authors reported common variant associations at 287 distinct genomic loci.

TL;DR: The association between white noise speech illusions and familial risk is contingent on additional evidence of endophenotypic expression and of exposure to childhood adversity, and speech illusions may represent a trait-dependent risk marker.

TL;DR: A review of the recent developments and how integrated, large-scale investigations may overcome contemporary challenges in G × E research can be found in this paper, drawing on the example of a large, international, multi-center study into the identification and translational application of gene-environment interactions in schizophrenia.

TL;DR: It is concluded that atypical antipsychotics do not represent a homogeneous class, and that differences in side effects should be taken into account by clinicians when choosing an antipsychotic for an individual patient.