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Eric Y.H. Chen

Researcher at University of Hong Kong

Publications -  439
Citations -  22941

Eric Y.H. Chen is an academic researcher from University of Hong Kong. The author has contributed to research in topics: Schizophrenia & Population. The author has an hindex of 55, co-authored 398 publications receiving 18748 citations. Previous affiliations of Eric Y.H. Chen include Queen Mary University of London & The Chinese University of Hong Kong.

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Biological insights from 108 schizophrenia-associated genetic loci

Stephan Ripke, +354 more
- 24 Jul 2014 - 
TL;DR: Associations at DRD2 and several genes involved in glutamatergic neurotransmission highlight molecules of known and potential therapeutic relevance to schizophrenia, and are consistent with leading pathophysiological hypotheses.
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Assessment of executive functions: review of instruments and identification of critical issues.

TL;DR: It is concluded that more research is needed to fractionate the executive system by assessing a wide range of functions and to verify their neuroanatomical correlates.
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Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Bjarni J. Vilhjálmsson, +394 more
TL;DR: LDpred is introduced, a method that infers the posterior mean effect size of each marker by using a prior on effect sizes and LD information from an external reference panel, and outperforms the approach of pruning followed by thresholding, particularly at large sample sizes.
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How mental health care should change as a consequence of the COVID-19 pandemic.

TL;DR: The interconnectedness of the world made society vulnerable to this infection, but it also provides the infrastructure to address previous system failings by disseminating good practices that can result in sustained, efficient, and equitable delivery of mental health-care delivery.
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Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Douglas M. Ruderfer, +631 more
- 14 Jun 2018 - 
TL;DR: For the first time, specific loci that distinguish between BD and SCZ are discovered and polygenic components underlying multiple symptom dimensions are identified that point to the utility of genetics to inform symptomology and potential treatment.