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Binyamin A. Knisbacher
Researcher at Broad Institute
Publications - 30
Citations - 1487
Binyamin A. Knisbacher is an academic researcher from Broad Institute. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 14, co-authored 20 publications receiving 1180 citations. Previous affiliations of Binyamin A. Knisbacher include Bar-Ilan University.
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Journal ArticleDOI
Corrigendum: Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax.
Xiaodong Fang,Eviatar Nevo,Lijuan Han,Erez Y. Levanon,Jing Zhao,Aaron Avivi,Denis M. Larkin,Xuanting Jiang,Sergey Feranchuk,Yabing Zhu,Alla Fishman,Yue Feng,Noa Sher,Zhiqiang Xiong,Thomas Hankeln,Zhiyong Huang,Vera Gorbunova,Lu Zhang,Wei Zhao,Derek E. Wildman,Derek E. Wildman,Yingqi Xiong,Andrei V. Gudkov,Qiumei Zheng,Gideon Rechavi,Sanyang Liu,Lily Bazak,Jie Chen,Jie Chen,Binyamin A. Knisbacher,Yao Lu,Imad Shams,Krzysztof Gajda,Marta Farré,Jaebum Kim,Harris A. Lewin,Jian Ma,Mark Band,Anne Bicker,Angela Kranz,Tobias Mattheus,Hanno Schmidt,Andrei Seluanov,Jorge Azpurua,Michael R. McGowen,Eshel Ben Jacob,Kexin Li,Shaoliang Peng,Xiaoqian Zhu,Xiangke Liao,Shuai Cheng Li,Anders Krogh,Xin Zhou,Leonid Brodsky,Jun Wang +54 more
TL;DR: In this paper, a Genome-Wide Adaptive Complex to underground stresses in blind mole rats Spalax is described, where the adaptive complexes are based on adaptive complexes to underground stress.
Journal ArticleDOI
Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors.
Nurit Paz-Yaacov,Lily Bazak,Ilana Buchumenski,Hagit T. Porath,Miri Danan-Gotthold,Binyamin A. Knisbacher,Eli Eisenberg,Erez Y. Levanon +7 more
TL;DR: It is shown that A-to-I editing and the enzymes mediating this modification are significantly altered, usually elevated, in most cancer types, and increased editing activity is found to be associated with patient survival.
Journal ArticleDOI
Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax
Xiaodong Fang,Eviatar Nevo,Lijuan Han,Erez Y. Levanon,Jing Zhao,Aaron Avivi,Denis M. Larkin,Xuanting Jiang,Sergey Feranchuk,Yabing Zhu,Alla Fishman,Yue Feng,Noa Sher,Zhiqiang Xiong,Thomas Hankeln,Zhiyong Huang,Vera Gorbunova,Lu Zhang,Wei Zhao,Derek E. Wildman,Yingqi Xiong,Andrei V. Gudkov,Qiumei Zheng,Gideon Rechavi,Sanyang Liu,Lily Bazak,Jie Chen,Binyamin A. Knisbacher,Yao Lu,Imad Shams,Krzysztof Gajda,Marta Farré,Jaebum Kim,Harris A. Lewin,Jian Ma,Mark Band,Anne Bicker,Angela Kranz,Tobias Mattheus,Hanno Schmidt,Andrei Seluanov,Jorge Azpurua,Michael R. McGowen,Eshel Ben Jacob,Kexin Li,Shaoliang Peng,Xiaoqian Zhu,Xiangke Liao,Shuai Cheng Li,Anders Krogh,Xin Zhou,Leonid Brodsky,Jun Wang,Jun Wang +53 more
TL;DR: The results show high rates of RNA/DNA editing, reduced chromosome rearrangements, an over-representation of short interspersed elements (SINEs) probably linked to Hypoxia tolerance, degeneration of vision and progression of photoperiodic perception, tolerance to hypercapnia and hypoxia and resistance to cancer.
Journal ArticleDOI
Massive A-to-I RNA editing is common across the Metazoa and correlates with dsRNA abundance
TL;DR: The method reveals a considerable variation in hyper-editing levels across species, which is partly explained by differences in the potential of sequences to form dsRNA structures and the variability of ADAR proteins.
Journal ArticleDOI
Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer.
Tamara Ouspenskaia,Travis Law,Karl R. Clauser,Susan Klaeger,Siranush Sarkizova,Siranush Sarkizova,François Aguet,Bo Li,Bo Li,Elena Christian,Binyamin A. Knisbacher,Phuong M. Le,Christina R. Hartigan,Hasmik Keshishian,Annie Apffel,Giacomo Oliveira,Wandi Zhang,Sarah Chen,Yuen Ting Chow,Zhe Ji,Irwin Jungreis,Irwin Jungreis,Sachet A. Shukla,Sachet A. Shukla,Sune Justesen,Pavan Bachireddy,Manolis Kellis,Manolis Kellis,Gad Getz,Nir Hacohen,Nir Hacohen,Derin B. Keskin,Steven A. Carr,Catherine J. Wu,Aviv Regev,Aviv Regev,Aviv Regev +36 more
TL;DR: In this article, a high-confidence database of translated nuORFs across tissues (nuORFdb) was constructed and used to detect 3,555 translated unicast ORFs from MHC-I immunopeptidome mass spectrometry analysis.