L
Lu Zhang
Researcher at Hong Kong Baptist University
Publications - 67
Citations - 2812
Lu Zhang is an academic researcher from Hong Kong Baptist University. The author has contributed to research in topics: Genome & Genome-wide association study. The author has an hindex of 17, co-authored 56 publications receiving 2329 citations. Previous affiliations of Lu Zhang include Li Ka Shing Faculty of Medicine, University of Hong Kong & Stanford University.
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Journal ArticleDOI
Whole-genome sequencing of cultivated and wild peppers provides insights into Capsicum domestication and specialization
Cheng Qin,Cheng Qin,Changshui Yu,Yaou Shen,Xiaodong Fang,Xiaodong Fang,Lang Chen,Jiumeng Min,Jiaowen Cheng,Shancen Zhao,Meng Xu,Yong Luo,Yulan Yang,Zhiming Wu,Likai Mao,Haiyang Wu,Changying Ling-Hu,Huangkai Zhou,Haijian Lin,Sandra Isabel González-Morales,Diana L. Trejo-Saavedra,Hao Tian,Xin Tang,Maojun Zhao,Zhiyong Huang,Anwei Zhou,Xiaoming Yao,Junjie Cui,Wenqi Li,Zhe Chen,Yongqiang Feng,Yongchao Niu,Shimin Bi,Xiuwei Yang,Weipeng Li,Huimin Cai,Xirong Luo,Salvador Montes-Hernández,Marco Antonio Leyva-González,Zhiqiang Xiong,Xiujing He,Lijun Bai,Shu Tan,Xiangqun Tang,Dan Liu,Jinwen Liu,Shangxing Zhang,Maoshan Chen,Lu Zhang,Lu Zhang,Li Zhang,Yinchao Zhang,Weiqin Liao,Yan Zhang,Min Wang,Xiaodan Lv,Bo Wen,Hongjun Liu,Hemi Luan,Yonggang Zhang,Shuang Yang,Xiaodian Wang,Jiaohui Xu,Xueqin Li,Shuai Cheng Li,Junyi Wang,Alain Palloix,Paul W. Bosland,Yingrui Li,Anders Krogh,Rafael F. Rivera-Bustamante,Luis Herrera-Estrella,Ye Yin,Jiping Yu,Kailin Hu,Zhiming Zhang +75 more
TL;DR: It is found that dosage compensation effect of tandem duplication genes probably contributed to the pungent diversification in pepper and the Capsicum reference genome provides crucial information for the study of not only the evolution of the pepper genome but also, the Solanaceae family.
Journal ArticleDOI
Corrigendum: Genome-wide adaptive complexes to underground stresses in blind mole rats Spalax.
Xiaodong Fang,Eviatar Nevo,Lijuan Han,Erez Y. Levanon,Jing Zhao,Aaron Avivi,Denis M. Larkin,Xuanting Jiang,Sergey Feranchuk,Yabing Zhu,Alla Fishman,Yue Feng,Noa Sher,Zhiqiang Xiong,Thomas Hankeln,Zhiyong Huang,Vera Gorbunova,Lu Zhang,Wei Zhao,Derek E. Wildman,Derek E. Wildman,Yingqi Xiong,Andrei V. Gudkov,Qiumei Zheng,Gideon Rechavi,Sanyang Liu,Lily Bazak,Jie Chen,Jie Chen,Binyamin A. Knisbacher,Yao Lu,Imad Shams,Krzysztof Gajda,Marta Farré,Jaebum Kim,Harris A. Lewin,Jian Ma,Mark Band,Anne Bicker,Angela Kranz,Tobias Mattheus,Hanno Schmidt,Andrei Seluanov,Jorge Azpurua,Michael R. McGowen,Eshel Ben Jacob,Kexin Li,Shaoliang Peng,Xiaoqian Zhu,Xiangke Liao,Shuai Cheng Li,Anders Krogh,Xin Zhou,Leonid Brodsky,Jun Wang +54 more
TL;DR: In this paper, a Genome-Wide Adaptive Complex to underground stresses in blind mole rats Spalax is described, where the adaptive complexes are based on adaptive complexes to underground stress.
Journal ArticleDOI
Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus.
Wanling Yang,Nan Shen,Dong-Qing Ye,Qiji Liu,Qiji Liu,Yan Zhang,Xiaoxia Qian,Nattiya Hirankarn,Dingge Ying,Hai-Feng Pan,Chi Chiu Mok,Tak Mao Chan,Raymond Woon Sing Wong,KW Lee,Mo Yin Mok,Sik Nin Wong,Alexander Moon Ho Leung,Xiang-Pei Li,Yingyos Avihingsanon,Chun-Ming Wong,Tsz Leung Lee,Marco Ho,Pamela Pui Wah Lee,Yuk Kwan Chang,Philip H. Li,Ruo-Jie Li,Ruo-Jie Li,Lu Zhang,Wilfred Hing Sang Wong,Irene Oi-Lin Ng,Chak Sing Lau,Pak C. Sham,Yu-Lung Lau +32 more
TL;DR: This study confirmed association of the HLA locus, STAT4, TNFSF4, BLK, BANK1, IRF5, and TNFAIP3 with SLE in Asians and found new genetic findings that may help gain a better understanding of the disease and the functions of the genes involved.
Journal ArticleDOI
Adaptation and possible ancient interspecies introgression in pigs identified by whole-genome sequencing.
Huashui Ai,Xiaodong Fang,Bin Yang,Zhiyong Huang,Hao Chen,Likai Mao,Feng Zhang,Lu Zhang,Leilei Cui,Weiming He,Jie Yang,Xiaoming Yao,Lisheng Zhou,Lijuan Han,Jing Li,Silong Sun,Xianhua Xie,Boxian Lai,Ying Su,Yao Lu,Hui Yang,Tao Huang,Wenjiang Deng,Rasmus Nielsen,Jun Ren,Lusheng Huang +25 more
TL;DR: An exceptionally large (14-Mb) region with a low recombination rate on the X chromosome is found that appears to have two distinct haplotypes in the high- and low-latitude populations, possibly underlying their adaptation to cold and hot environments, respectively.
Journal ArticleDOI
Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians
Wanling Yang,Huayang Tang,Yan Zhang,Xianfa Tang,Jing Zhang,Liangdan Sun,Jing Yang,Yong Cui,Lu Zhang,Nattiya Hirankarn,Hui Cheng,Hai-Feng Pan,Jinping Gao,Tsz Leung Lee,Yujun Sheng,Chak Sing Lau,Yang Li,Tak Mao Chan,Xianyong Yin,Dingge Ying,Qianjin Lu,Alexander Moon Ho Leung,Xianbo Zuo,Xiang Chen,Kwok Lung Tong,Fusheng Zhou,Qingchun Diao,Niko Kei Chiu Tse,Hongfu Xie,Chi Chiu Mok,Fei Hao,Sik Nin Wong,Bingjun Shi,KW Lee,Yan Hui,Marco Ho,Bo Liang,Pamela Pui Wah Lee,Hongzhou Cui,Qing Guo,Brian H.Y. Chung,Xiong-Ming Pu,Qiji Liu,Xiaoguang Zhang,Change Zhang,Chun Yin Chong,Hong Fang,Raymond Woon Sing Wong,Yonghu Sun,Mo Yin Mok,Xiang-Pei Li,Yingyos Avihingsanon,Zhifang Zhai,Pornpimol Rianthavorn,Thavatchai Deekajorndej,Kanya Suphapeetiporn,Kanya Suphapeetiporn,Fei Gao,Vorasuk Shotelersuk,Vorasuk Shotelersuk,Xiao-Jing Kang,Shirley King Yee Ying,Li Juan Zhang,Wilfred Hing Sang Wong,Dingxian Zhu,Samuel Ka Shun Fung,Fanqin Zeng,Wai Ming Lai,Chun-Ming Wong,Irene Oi-Lin Ng,Maria-Mercè Garcia-Barceló,Stacey S. Cherny,Nan Shen,Paul K.H. Tam,Pak C. Sham,Dong-Qing Ye,Sen Yang,Xuejun Zhang,Yu-Lung Lau +78 more
TL;DR: Genetic variants in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B are identified as associated with SLE and point to potential roles of cell-cycle regulation, autophagy, and DNA demethylation in SLE pathogenesis.