C
Christine Schmäl
Researcher at Heidelberg University
Publications - 26
Citations - 1748
Christine Schmäl is an academic researcher from Heidelberg University. The author has contributed to research in topics: Genome-wide association study & Bipolar disorder. The author has an hindex of 16, co-authored 25 publications receiving 1587 citations. Previous affiliations of Christine Schmäl include University of Mannheim & University of Bonn.
Papers
More filters
Journal ArticleDOI
Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression.
Johannes Schumacher,Rami Abou Jamra,Tim Becker,Stephanie Ohlraun,Norman Klopp,Elisabeth B. Binder,Thomas G. Schulze,Monika Deschner,Christine Schmäl,Susanne Höfels,Astrid Zobel,Thomas Illig,Peter Propping,Florian Holsboer,Marcella Rietschel,Markus M. Nöthen,Markus M. Nöthen,Sven Cichon,Sven Cichon +18 more
TL;DR: The findings suggest that BDNF may be a susceptibility gene for MDD and schizophrenia-in particular, in a subgroup of patients with schizophrenia with a lifetime history of depressive symptoms.
Journal ArticleDOI
Genome-wide Association Study Identifies Genetic Variation in Neurocan as a Susceptibility Factor for Bipolar Disorder
Sven Cichon,Thomas W. Mühleisen,Franziska Degenhardt,Manuel Mattheisen,Xavier Miró,Jana Strohmaier,Michael Steffens,Christian Meesters,Stefan Herms,Moritz Weingarten,Lutz Priebe,Britta Haenisch,Michael Alexander,Jennifer Vollmer,René Breuer,Christine Schmäl,Peter Tessmann,Susanne Moebus,H.-Erich Wichmann,Stefan Schreiber,Bertram Müller-Myhsok,Susanne Lucae,Stéphane Jamain,Stéphane Jamain,Marion Leboyer,Marion Leboyer,Frank Bellivier,Frank Bellivier,Bruno Etain,Bruno Etain,Chantal Henry,Chantal Henry,Jean-Pierre Kahn,Simon Heath,Marian L. Hamshere,Michael Conlon O'Donovan,Michael John Owen,Nicholas John Craddock,Markus J. Schwarz,Helmut Vedder,Jutta Kammerer-Ciernioch,Andreas Reif,Johanna Sasse,Michael Bauer,Martin Hautzinger,Adam Wright,Adam Wright,Philip B. Mitchell,Philip B. Mitchell,Peter R. Schofield,Peter R. Schofield,Grant W. Montgomery,Sarah E. Medland,Scott D. Gordon,Nicholas G. Martin,Omar Gustafsson,Ole A. Andreassen,Ole A. Andreassen,Srdjan Djurovic,Srdjan Djurovic,Engilbert Sigurdsson,Stacy Steinberg,Hreinn Stefansson,Kari Stefansson,Kari Stefansson,Lejla Kapur-Pojskić,Liliana Oruc,Fabio Rivas,Fermín Mayoral,Alexander Chuchalin,Gulja Babadjanova,Alexander S. Tiganov,Galina Pantelejeva,Lilia I. Abramova,Maria Grigoroiu-Serbanescu,Carmen C. Diaconu,Piotr M. Czerski,Joanna Hauser,Andreas Zimmer,Mark Lathrop,Thomas G. Schulze,Thomas F. Wienker,Johannes Schumacher,Wolfgang Maier,Peter Propping,Marcella Rietschel,Markus M. Nöthen +86 more
TL;DR: Evidence is provided that NCAN encodes neurocan, an extracellular matrix glycoprotein, which is thought to be involved in cell adhesion and migration, and expression in mice is localized within cortical and hippocampal areas.
Journal ArticleDOI
Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression.
Marcella Rietschel,Manuel Mattheisen,Josef Frank,Jens Treutlein,Franziska Degenhardt,René Breuer,Michael Steffens,Daniela Mier,Christine Esslinger,Henrik Walter,Peter Kirsch,Susanne Erk,Knut Schnell,Stefan Herms,H.-Erich Wichmann,Stefan Schreiber,Karl-Heinz Jöckel,Jana Strohmaier,D. Roeske,Britta Haenisch,Magdalena Gross,Susanne Hoefels,Susanne Lucae,Elisabeth B. Binder,Thomas F. Wienker,Thomas G. Schulze,Christine Schmäl,Andreas Zimmer,Dilafruz Juraeva,Benedikt Brors,Thomas Bettecken,Andreas Meyer-Lindenberg,Bertram Müller-Myhsok,Wolfgang Maier,Markus M. Nöthen,Sven Cichon +35 more
TL;DR: The findings of this genome-wide association study suggest that HOMER1 plays a role in the etiology of major depression and that the genetic variation affects depression via the dysregulation of cognitive and motivational processes.
Journal ArticleDOI
Genome-wide significant association between alcohol dependence and a variant in the ADH gene cluster.
Josef Frank,Sven Cichon,Sven Cichon,Jens Treutlein,Monika Ridinger,Manuel Mattheisen,Manuel Mattheisen,Per Hoffmann,Stefan Herms,Norbert Wodarz,Michael Soyka,Peter Zill,Wolfgang Maier,Rainald Mössner,Wolfgang Gaebel,Norbert Dahmen,Norbert Scherbaum,Christine Schmäl,Michael Steffens,Susanne Lucae,Marcus Ising,Bertram Müller-Myhsok,Markus M. Nöthen,Karl Mann,Falk Kiefer,Marcella Rietschel +25 more
TL;DR: This is the first GWAS of AD to provide genome‐wide significant support for the role of the ADH gene cluster and to suggest a polygenic component to the etiology of AD.
Journal ArticleDOI
Genetics of dyslexia: the evolving landscape
TL;DR: Results indicate that a disturbance in neuronal migration is a pathological correlate of dyslexia at the functional level and an overview of anticipated future developments is presented.