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Edythe D. London

Researcher at University of California, Los Angeles

Publications -  492
Citations -  36481

Edythe D. London is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Nicotinic agonist & Methamphetamine. The author has an hindex of 93, co-authored 482 publications receiving 33741 citations. Previous affiliations of Edythe D. London include Icahn School of Medicine at Mount Sinai & Semel Institute for Neuroscience and Human Behavior.

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Differential effects of age on motor performance in two mouse strains

TL;DR: The performance of male A/J and C57BL/6J mice from three age groups was observed in a battery of tests designed to assess age-related impairments in motor abilities, and the results underscore the need to consider genotype in the assessment of age- related motor impairments.
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Nicotinic binding sites in cerebral cortex and hippocampus in Alzheimer's dementia.

TL;DR: A loss of neocortical and hippocampal nicotinic cholinergic binding sites in DAT is supported, and correlations between binding of the two ligands were statistically significant in control and DAT groups.
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Development of ligands for in vivo imaging of cerebral nicotinic receptors

TL;DR: Three general classes of compounds, namely, nicotine and its analogs, epibatidine and related compounds, and 3-pyridyl ether compounds, including A-85380 appear to be the most promising candidates because of their low toxicity and high selectivity for the alpha4beta2 subtype of nAChRs.