E
Edythe D. London
Researcher at University of California, Los Angeles
Publications - 492
Citations - 36481
Edythe D. London is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Nicotinic agonist & Methamphetamine. The author has an hindex of 93, co-authored 482 publications receiving 33741 citations. Previous affiliations of Edythe D. London include Icahn School of Medicine at Mount Sinai & Semel Institute for Neuroscience and Human Behavior.
Papers
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Journal ArticleDOI
A neural network that links brain function, white-matter structure and risky behavior.
TL;DR: The present findings provide the first direct evidence that white‐matter integrity is linked to function within previously identified components of a network that is activated during risky decision‐making, and demonstrate that the integrity ofwhite‐matter tracts is critical in consolidating and processing signals between cortical and striatal circuits during the decision-making process.
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Parental substance abuse and function of the motivation and behavioral inhibition systems in drug-naïve youth.
Iliyan Ivanov,Xun Liu,Kurt Shulz,Jin Fan,Edythe D. London,Karl J. Friston,Jeffrey M. Halperin,Jeffrey M. Halperin,Jeffrey H. Newcorn +8 more
TL;DR: In this paper, the authors used functional magnetic resonance imaging (fMRI) in drug-naive youth with attention deficit/hyperactivity disorder (ADHD) and found that children with ADHD alone would show higher activation in regions of the motivation-reward and behavioral inhibition systems than those with ADHD and a parental history of addiction.
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Cigarette Use and Striatal Dopamine D2/3 Receptors: Possible Role in the Link between Smoking and Nicotine Dependence
TL;DR: An effect of smoking on ventral striatal D2/3 dopamine receptors that may contribute to nicotine dependence is suggested.
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Thalamic glutamate decreases with cigarette smoking.
Joseph O'Neill,Marc Tobias,Matthew Hudkins,Eugene Y. Oh,Gerhard Hellemann,Erika L. Nurmi,Edythe D. London,Edythe D. London +7 more
TL;DR: Within smokers, cigarettes/day and pack-years are associated with reduced Glu in thalamus, a brain region rich in nAchRs, which encourages work on candidate glutamatergic therapies for smoking cessation and suggests a noninvasive metric for their action in the brain.
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Postischemic brain injury is affected stereospecifically by pentazocine in rats.
TL;DR: Data indicate that sigma1-receptors may play an important role in the mechanism of injury both in cortex and striatum after 2 h of transient focal ischemia in rat.