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Edythe D. London

Researcher at University of California, Los Angeles

Publications -  492
Citations -  36481

Edythe D. London is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Nicotinic agonist & Methamphetamine. The author has an hindex of 93, co-authored 482 publications receiving 33741 citations. Previous affiliations of Edythe D. London include Icahn School of Medicine at Mount Sinai & Semel Institute for Neuroscience and Human Behavior.

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Extraordinary postmortem stability of kappa opioid receptors in guinea-pig brain

TL;DR: The remarkable stability of kappa receptors may greatly facilitate the study of this opioid receptor subtype in human brain, as subjected guineapig brains to gradual cooling, simulating temperature conditions of human postmortem brains.
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Executive function moderates naltrexone effects on methamphetamine-induced craving and subjective responses

TL;DR: Naltrexone may be especially effective in methamphetamine-dependent individuals with low EF, and neuropsychological assessments may also provide predictive clinical utility not captured by traditional measures of substance use severity.
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Self-awareness of problematic drug use: Preliminary validation of a new fMRI task to assess underlying neurocircuitry.

TL;DR: As a group, individuals with current CUD appear to show mild insight problems and rACC/vmPFC abnormalities vis-à-vis readiness to change behavior, with replication and extension of these results suggesting insight-related circuitry may emerge as a novel therapeutic target.