E
Edythe D. London
Researcher at University of California, Los Angeles
Publications - 492
Citations - 36481
Edythe D. London is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Nicotinic agonist & Methamphetamine. The author has an hindex of 93, co-authored 482 publications receiving 33741 citations. Previous affiliations of Edythe D. London include Icahn School of Medicine at Mount Sinai & Semel Institute for Neuroscience and Human Behavior.
Papers
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Journal ArticleDOI
Age and strain comparisons of neurotransmitter synthetic enzyme activities in the mouse.
TL;DR: It is indicated that neurochemical profiles as well as the effects of age on these profiles vary with genetic strain, and that hippocampal ChAT and GAD and cerebellar TH in older C57BL/6J mice reflected increases in Vmax, with no age differences in Km values for substrates.
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Palmitate incorporation into different brain regions in the awake rat.
TL;DR: The results demonstrate that it is possible to determine unidirectional palmitate flux into a stable metabolic compartment in individual brain regions of awake rats, that flux into gray matter regions generally exceeds flux into white matter, and that palMITate flux is proportional to published values for regional brain oxidative metabolism.
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Radiosynthesis and preliminary evaluation of 5-[123/125I]iodo-3-(2(S)-azetidinylmethoxy)pyridine: a radioligand for nicotinic acetylcholine receptors
Andrew G. Horti,Andrei O. Koren,Kan Sam Lee,Alexey G. Mukhin,D. Bruce Vaupel,Alane S. Kimes,Morgan Stratton,Edythe D. London +7 more
TL;DR: Preliminary in vivo assay and ex vivo autoradiography of mouse brain indicated that [125I]1 selectively labels nicotinic acetylcholine receptors (nAChRs) with very high affinity and specificity, and studies suggest that [123I] 1 may be useful as a radioligand for single photon emission computed tomography (SPECT) imaging of nA ChRs.
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Effect of Cigarette Smoking on Prefrontal Cortical Function in Nondeprived Smokers Performing the Stroop Task
Jiansong Xu,Adrianna Mendrek,Mark S. Cohen,John Monterosso,Sara L. Simon,Murray E. Jarvik,Richard G. Olmstead,Arthur L. Brody,Monique Ernst,Edythe D. London +9 more
TL;DR: Even after brief abstinence from smoking, smokers exhibit compromised functional efficiency in the right FEF and adjacent precentral sulcus in a test of selective attention; and smoking ameliorates this condition.
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Cannabis effects on brain structure, function, and cognition: considerations for medical uses of cannabis and its derivatives.
TL;DR: A review of relevant findings in order to inform attitudes and public policy regarding the recreational and medical use of cannabis and cannabinoid compounds and to point to considerations for age limits and guidelines for use.