E
Edythe D. London
Researcher at University of California, Los Angeles
Publications - 492
Citations - 36481
Edythe D. London is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Nicotinic agonist & Methamphetamine. The author has an hindex of 93, co-authored 482 publications receiving 33741 citations. Previous affiliations of Edythe D. London include Icahn School of Medicine at Mount Sinai & Semel Institute for Neuroscience and Human Behavior.
Papers
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Journal ArticleDOI
Decision-making and facial emotion recognition as predictors of substance-use initiation among adolescents.
Monique Ernst,David A. Luckenbaugh,Eric T. Moolchan,Veronica Temple,Jessica L. Jenness,Katherine E. Korelitz,Edythe D. London,Alane S. Kimes +7 more
TL;DR: It is concluded that adolescents who initiate drug use present vulnerability in the form of bias towards negative emotion but not toward decisions that involve risk.
Journal ArticleDOI
Diminished neurokinin-1 receptor availability in patients with two forms of chronic visceral pain
Johanna M. Jarcho,Natasha A. Feier,Natasha A. Feier,Alberto Bert,Jennifer A. Labus,Maunoo Lee,Jean Stains,Bahar Ebrat,Stephanie M. Groman,Kirsten Tillisch,Arthur L. Brody,Edythe D. London,M. Mandelkern,Emeran A. Mayer +13 more
TL;DR: Widespread deficits in NK‐1R BP occur in IBD and, to a lesser extent, IBS; however, discrete clinical parameters relate to NK‐ 1R BP in each patient population, suggesting that potential pharmacological interventions that target NK-1R signaling may be most effective for treating distinct symptoms in I BD and IBS.
Journal ArticleDOI
Age-related decline in striatal volume in rhesus monkeys: assessment of long-term calorie restriction
John A. Matochik,Svetlana I. Chefer,Mark A. Lane,George S. Roth,Julie A. Mattison,Edythe D. London,Donald K. Ingram +6 more
TL;DR: Volumes of the putamen (not the caudate nucleus) were larger bilaterally in the CON than in the CR group both at middle age and senescence, and regression analysis indicated bilateral age-related declines in putamen and caudates nucleus volumes in the old CON monkeys.
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Baseline impulsivity may moderate L-DOPA effects on value-based decision-making
Johannes Petzold,Annika Kienast,Annika Kienast,Ying Lee,Shakoor Pooseh,Shakoor Pooseh,Edythe D. London,Thomas Goschke,Michael N. Smolka +8 more
TL;DR: In support of the hypothesis of an inverted U-shaped dopamine function in which both low and high extremes of dopamine signaling are associated with high-impulsive choice, consideration of differential baseline impulsivity and body weight may deepen the understanding of dopaminergic mechanisms underlying impulsivity.
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Sex Differences in Midbrain Dopamine D2-Type Receptor Availability and Association with Nicotine Dependence
Kyoji Okita,Nicole Petersen,Chelsea L. Robertson,Andy C. Dean,M. Mandelkern,Edythe D. London +5 more
TL;DR: A sex difference is suggested in how midbrain dopamine D2-type autoreceptors in the midbrain influence striatal dopamine release, a function that has been linked to addiction, and in relationships between midbrain BPND, nicotine dependence and striatal Parkinson's disease receptor BPND.