E
Edythe D. London
Researcher at University of California, Los Angeles
Publications - 492
Citations - 36481
Edythe D. London is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Nicotinic agonist & Methamphetamine. The author has an hindex of 93, co-authored 482 publications receiving 33741 citations. Previous affiliations of Edythe D. London include Icahn School of Medicine at Mount Sinai & Semel Institute for Neuroscience and Human Behavior.
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Journal ArticleDOI
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
Joey W. Trampush,M. L. Z. Yang,Jin Yu,Emma Knowles,Gary Davies,David C. Liewald,John M. Starr,Srdjan Djurovic,Srdjan Djurovic,Ingrid Melle,Ingrid Melle,Kjetil Sundet,Andrea Christoforou,Andrea Christoforou,Ivar Reinvang,Pamela DeRosse,Astri J. Lundervold,Vidar M. Steen,Vidar M. Steen,Thomas Espeseth,Katri Räikkönen,Elisabeth Widen,Aarno Palotie,Aarno Palotie,Johan G. Eriksson,Ina Giegling,Bettina Konte,Panos Roussos,Panos Roussos,Stella G. Giakoumaki,Katherine E. Burdick,Katherine E. Burdick,Antony Payton,Antony Payton,William E R Ollier,Michael A Horan,Ornit Chiba-Falek,Deborah K. Attix,Anna C. Need,Elizabeth T. Cirulli,Aristotle N. Voineskos,Nicholas C. Stefanis,Nicholas C. Stefanis,Dimitrios Avramopoulos,Alex Hatzimanolis,Alex Hatzimanolis,Dan E. Arking,Nikolaos Smyrnis,Nikolaos Smyrnis,Robert M. Bilder,Nelson A. Freimer,Tyrone D. Cannon,Edythe D. London,Russell A. Poldrack,Fred W. Sabb,Eliza Congdon,Emily Drabant Conley,Matthew A. Scult,Dwight Dickinson,Richard E. Straub,Gary Donohoe,Derek W. Morris,Aiden Corvin,M. Gill,Ahmad R. Hariri,Daniel R. Weinberger,Neil Pendleton,Panos Bitsios,Dan Rujescu,Jari Lahti,S. Le Hellard,Matthew C. Keller,Ole A. Andreassen,Ole A. Andreassen,Ole A. Andreassen,Ian J. Deary,David C. Glahn,Anil K. Malhotra,Anil K. Malhotra,Todd Lencz,Todd Lencz +80 more
TL;DR: Common variation across the genome resulted in a conservatively estimated SNP heritability of 21.5% for general cognitive function, which provides new insight into the genetics of neurocognitive function with relevance to understanding the pathophysiology of neuropsychiatric illness.
Journal ArticleDOI
An Evaluation of the Evidence that Methamphetamine Abuse Causes Cognitive Decline in Humans
TL;DR: The preponderance of the data does support the possibility that MA abuse causes cognitive decline, of unknown duration, in at least some users of the drug, when averaged across individuals.
Journal ArticleDOI
Regulation of the NMDA receptor by redox phenomena: inhibitory role of ascorbate.
TL;DR: Redox phenomena seem to modulate activity of the N-methyl-D-aspartate receptor, which abolishes the ability of reductants to alter function of the NMDA receptor.
Journal ArticleDOI
Mega-Analysis of Gray Matter Volume in Substance Dependence: General and Substance-Specific Regional Effects
Scott Mackey,Nicholas Allgaier,Bader Chaarani,Philip A. Spechler,Catherine Orr,Janice Bunn,Nicholas B. Allen,Nelly Alia-Klein,Albert Batalla,Sara K. Blaine,Samantha J. Brooks,Elisabeth C. Caparelli,Yann Chye,Janna Cousijn,Alain Dagher,Sylvane Desrivières,Sarah W. Feldstein-Ewing,John J. Foxe,Rita Z Goldstein,Anna E Goudriaan,Mary M. Heitzeg,Robert Hester,Kent E. Hutchison,Ozlem Korucuoglu,Chiang-Shan R. Li,Edythe D. London,Valentina Lorenzetti,Maartje Luijten,R. Martin-Santos,April C. May,Reza Momenan,Angelica M. Morales,Martin P. Paulus,Godfrey D. Pearlson,M. Rousseau,Betty Jo Salmeron,Renée S. Schluter,Lianne Schmaal,Gunter Schumann,Zsuzsika Sjoerds,Dan J. Stein,Elliot A. Stein,Rajita Sinha,Nadia Solowij,Susan F. Tapert,Anne Uhlmann,Dick J. Veltman,Ruth J. van Holst,Sarah Whittle,Margaret J. Wright,Murat Yücel,Sheng Zhang,Deborah A. Yurgelun-Todd,Derrek P. Hibar,Neda Jahanshad,Alan C. Evans,Paul M. Thompson,David C. Glahn,Patricia J. Conrod,Hugh Garavan +59 more
TL;DR: The results indicate that dependence on a range of different substances shares a common neural substrate and that differential patterns of regional volume could serve as useful biomarkers of dependence on alcohol and nicotine.
Journal ArticleDOI
Effect of nicotine on brain activation during performance of a working memory task
Monique Ernst,John A. Matochik,Stephen J. Heishman,John D. Van Horn,Peter H. Jons,Jack E. Henningfield,Edythe D. London +6 more
TL;DR: The lateralization of activation as a function of nicotine dependence suggests that chronic exposure to nicotine or withdrawal from nicotine affects cognitive strategies used to perform the memory task.