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Edythe D. London

Researcher at University of California, Los Angeles

Publications -  492
Citations -  36481

Edythe D. London is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Nicotinic agonist & Methamphetamine. The author has an hindex of 93, co-authored 482 publications receiving 33741 citations. Previous affiliations of Edythe D. London include Icahn School of Medicine at Mount Sinai & Semel Institute for Neuroscience and Human Behavior.

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Attenuation of cue-induced cigarette craving and anterior cingulate cortex activation in bupropion-treated smokers: a preliminary study

TL;DR: Bupropion-treated smokers had smaller cigarette cue-induced increases in craving scores on the Urge to Smoke (UTS) Scale and less activation of perigenual/ventral ACC metabolism from the neutral to the cigarette cue scan than untreated smokers, consistent with the known effects of bupropion HCl, including its enhancement of catecholaminergic neurotransmission.
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Risky decision making and the anterior cingulate cortex in abstinent drug abusers and nonusers.

TL;DR: Both drug abusers and controls exhibited significant activations in a widespread network of brain regions, primarily in the frontal cortex, previously implicated in decision-making tasks, which underlie the abusers' tendency to choose risky outcomes.

GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium

Joey W. Trampush, +80 more
TL;DR: In this article, the association of common genetic variation (8M single-nucleotide polymorphisms with minor allele frequency ⩾ 1%) to general cognitive function in a sample of 35,298 healthy individuals of European ancestry across 24 cohorts in the Cognitive Genomics Consortium (COGENT) was examined.
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Synthetic Cathinone and Cannabinoid Designer Drugs Pose a Major Risk for Public Health.

TL;DR: Given the rapid increase in the use of synthetic cathinones and cannabinoid designer drugs, their potential for dependence and abuse, and harmful medical and psychiatric effects, there is a need for research and education in the areas of prevention and treatment.
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The Neuropsychiatry of Chronic Cocaine Abuse

TL;DR: Evidence is presented suggesting that cocaine abusers have specific dysfunction of executive functions (decision making, judgment) and that this behavior is associated with dysfunction of specific prefrontal brain regions, the orbitofrontal cortex, and anterior cingulate gyrus.