E
Edythe D. London
Researcher at University of California, Los Angeles
Publications - 492
Citations - 36481
Edythe D. London is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Nicotinic agonist & Methamphetamine. The author has an hindex of 93, co-authored 482 publications receiving 33741 citations. Previous affiliations of Edythe D. London include Icahn School of Medicine at Mount Sinai & Semel Institute for Neuroscience and Human Behavior.
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Journal ArticleDOI
Reduction of cerebral glucose utilization by the HIV envelope glycoprotein Gp-120
TL;DR: The findings suggest that gp-120 and closely related peptides can alter neuronal function, thereby contributing to the sequelae of HIV infection.
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Divergent ontogeny of sigma and phencyclidine binding sites in the rat brain.
TL;DR: The postnatal developmental patterns of sigma (sigma) and phencyclidine (PCP) binding sites were compared in the rat brain to provide evidence for distinctive properties of cerebral sigma and PCP binding sites.
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Pharmacological and Toxicological Evaluation of 2-Fluoro-3-(2(S)-azetidinylmethoxy)pyridine (2-F-A-85380), a Ligand for Imaging Cerebral Nicotinic Acetylcholine Receptors with Positron Emission Tomography
D. Bruce Vaupel,Srihari R. Tella,David L. Huso,Valentine O. Wagner,Alexey G. Mukhin,Svetlana I. Chefer,Andrew G. Horti,Edythe D. London,Andrei O. Koren,Alane S. Kimes +9 more
TL;DR: Dosimetry studies indicated that the urinary bladder wall was the critical organ and total radiation exposure was within acceptable limits, and the estimated radiopharmaceutically relevant dose of [18F]2-F-A-8380 required for initial PET imaging studies is less than 1/4000th of the doses calculated.
Journal Article
Midbrain Functional Connectivity and Ventral Striatal Dopamine D2-type Receptors: Link to Impulsivity in Methamphetamine Users
Milky Kohno,Chelsea L. Robertson,Kyoji Okita,Angelica M. Morales,Andy C. Dean,Dara G. Ghahremani,Fred W. Sabb,Richard A. Rawson,Mark A. Mandelkern,Robert M. Bilder,Edythe D. London +10 more
TL;DR: Results indicate that ventral striatal D2-type receptor signaling may affect the system-level activity within the mesocorticolimbic system, providing a functional link that may help explain high impulsivity in methamphetamine-dependent individuals.
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Choline acetyltransferase activity and muscarinic binding in brain regions of aging fischer-344 rats.
TL;DR: The findings have implications for use of the Fischer-344 male rat as an animal model of aging and age-related disorders of the human brain, including dementia of the Alzheimer type.