F
Fabien Zoulim
Researcher at French Institute of Health and Medical Research
Publications - 716
Citations - 40988
Fabien Zoulim is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Hepatitis B virus & Hepatitis B. The author has an hindex of 96, co-authored 641 publications receiving 35807 citations. Previous affiliations of Fabien Zoulim include Hotel Dieu Hospital & University of Orléans.
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Journal ArticleDOI
Entecavir plus tenofovir combination therapy for chronic hepatitis B in patients with previous nucleos(t)ide treatment failure
Fabien Zoulim,Jolanta Białkowska-Warzecha,Mircea Diculescu,Adrian Goldis,Renate Heyne,Tomasz Mach,Patrick Marcellin,Patrick Marcellin,Jörg Petersen,Krzysztof Simon,Soumaya Bendahmane,I. Klauck,Wojciech Wasiak,Harry L.A. Janssen,Harry L.A. Janssen +14 more
TL;DR: In NUC-experienced patients who have failed prior NUC therapy, ETV/TDF was well tolerated and effective, achieving virologic suppression through 96 weeks in the majority (85 %), irrespective of prior N UC exposure, without occurrence of treatment-emergent resistance to either agent.
Journal Article
Réactivation virale B après greffe de moelle allogénique chez un malade précédemment guéri d'une hépatite virale B.
TL;DR: Un traitement par ganciclovir a permis de controler l'hepatite aigue et d'obtenir l'arret de the replication virale lorsque est constatee une baisse progressive des titres d'anticorps protecteurs.
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Selective detection of human hepatitis B virus surface and core antigens in peripheral blood mononuclear cell subsets by flow cytometry
Isabelle Chemin,C. Vermot-Desroches,I. Baginski,J. C. Saurin,Frédéric Laurent,Fabien Zoulim,J. Bernaud,J. P. Lamelin,Olivier Hantz,D. Rigal,C. Trepo +10 more
TL;DR: It is demonstrated that replication and transcription of the HBV can occur in CD19‐ and CD56‐positive cells.
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Non-virological factors are drivers of hepatocellular carcinoma in virosuppressed hepatitis B cirrhosis: Results of ANRS CO12 CirVir cohort
Ségolène Brichler,Pierre Nahon,Fabien Zoulim,Richard Layese,Valérie Bourcier,Etienne Audureau,Angela Sutton,Eric Letouzé,Carole Cagnot,Patrick Marcellin,Dominique Guyader,Dominique Roulot,Stanislas Pol,Victor de Ledinghen,Jean-Pierre Zarski,Paul Calès,Albert Tran,Jean-Marie Péron,Ariane Mallat,Ghassan Riachi,Jean-Didier Grangé,Jean-Frédéric Blanc,Yannick Bacq,Denis Ouzan,Jean-Pierre Bronowicki,Philippe Mathurin,Dominique Larrey,Laurent Alric,Pierre Attali,Lawrence Serfaty,Christophe Pilette,Marc Bourlière,Dominique Thabut,Christine Silvain,Claire Wartelle,David Zucman,Christos Christidis,Françoise Roudot-Thoraval,Nathalie Ganne-Carrié +38 more
TL;DR: In French patients with HBV cirrhotic patients mostly virally suppressed, independent HCC risk factors were host‐related (age, obesity) or linked to the severity of cirrhosis (thrombopenia), and the European PAGE‐B score was the most accurate risk score.
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Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response.
Thomas Lahlali,M.-L. Plissonnier,Cristina Romero-López,Maud Michelet,Benjamin Ducarouge,Alfredo Berzal-Herranz,Fabien Zoulim,Patrick Mehlen,Romain Parent +8 more
TL;DR: UPR-resistant, internal ribosome entry site–driven netrin-1 translation leads to the inhibition of uncoordinated phenotype-5/death-associated protein kinase 1–mediated apoptosis in the hepatic context during UPR, a hallmark of chronic liver disease.